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前部电生理不对称、情绪与抑郁:概念及方法学难题

Anterior electrophysiological asymmetries, emotion, and depression: conceptual and methodological conundrums.

作者信息

Davidson R J

机构信息

Laboratory for Affective Neuroscience, University of Wisconsin-Madison 53706, USA.

出版信息

Psychophysiology. 1998 Sep;35(5):607-14. doi: 10.1017/s0048577298000134.

DOI:10.1017/s0048577298000134
PMID:9715104
Abstract

Two reports in the last issue of this journal attempted to replicate aspects of our previous studies on anterior electroencephalogram (EEG) asymmetry, affective style, and depression. In this commentary, an overview is provided of our model of anterior asymmetries, affective style, and psychopathology. Emphasis is placed on conceptualizing the prefrontal and anterior temporal activation patterns within a circuit that includes cortical and subcortical structures. The causal status of individual differences in asymmetric activation in the production of affective style and psychopathology is considered. Major emphasis is placed on EEG methods, particularly the need for multiple assessments to obtain estimates of asymmetric activation that better reflect an individual's true score. Issues specific to each of the two articles are also considered. Each of the articles has more consistency with our previously published data than the authors themselves suggest. Recommendations are made for future research to resolve some of the outstanding issues.

摘要

本刊上一期的两篇报告试图重复我们之前关于脑电图(EEG)前侧不对称、情感风格和抑郁症研究的某些方面。在这篇评论中,我们概述了前侧不对称、情感风格和精神病理学的模型。重点在于将前额叶和颞叶前部的激活模式在一个包括皮质和皮质下结构的回路中进行概念化。我们考虑了不对称激活的个体差异在情感风格和精神病理学产生中的因果地位。主要重点放在脑电图方法上,特别是需要进行多次评估以获得能更好反映个体真实分数的不对称激活估计值。我们还考虑了两篇文章各自的具体问题。每篇文章与我们之前发表的数据的一致性都比作者自己所认为的更高。我们为未来的研究提出了建议,以解决一些突出问题。

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