Weinstein R A, Emori T G, Anderson R L, Stamm W E
Chest. 1976 Mar;69(3):338-44. doi: 10.1378/chest.69.3.338.
During four weeks in 1974, eight (26 percent) of 31 intensive care unit patients who had undergone open-heart surgery developed symptomatic Pseudomonas cepacia bacteremia in the intensive care unit one to three days after the open-heart surgery. An investigation demonstrated that operating room pressure transducers were being contaminated during cleaning with a detergent that contained P cepacia at the rate of 10(4) organisms per milliliter and that the organisms were transmitted to patients after open-heart surgery as a result of one to three days of contact with transducer-monitoring lines used in the operating room and brought to the intensive care unit with the patient. Pressure-transducer contamination, a frequently unappreciated but preventable cause of nosocomial bacteremia, can be minimized by sterilizing transducers between use on different patients by paying strict attention to aseptic technique when setting up, calibrating, and using monitoring systems; and by changing transducers, tubing, and monitoring fluid for each monitored patient at regular intervals.
1974年的四周内,31名接受心脏直视手术的重症监护病房患者中有8名(26%)在心脏直视手术后1至3天于重症监护病房发生了有症状的洋葱伯克霍尔德菌菌血症。一项调查表明,手术室压力传感器在用含每毫升10⁴个洋葱伯克霍尔德菌的洗涤剂清洁时受到污染,这些细菌在心脏直视手术后通过与手术室使用的传感器监测线路接触1至3天而传播给患者,并随患者被带到重症监护病房。压力传感器污染是医院获得性菌血症一个常未被认识但可预防的原因,通过在不同患者使用之间对传感器进行消毒、在设置、校准和使用监测系统时严格注意无菌技术,以及定期为每个受监测患者更换传感器、管道和监测液,可将其危害降至最低。