4-羟基苯甲酸：露兜树根水提取物中的一种降血糖成分。
4-Hydroxybenzoic acid: a hypoglycemic constituent of aqueous extract of Pandanus odorus root.
作者信息
Peungvicha P, Temsiririrkkul R, Prasain J K, Tezuka Y, Kadota S, Thirawarapan S S, Watanabe H
机构信息
Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
出版信息
J Ethnopharmacol. 1998 Aug;62(1):79-84. doi: 10.1016/s0378-8741(98)00061-0.
PMID:9720616
Abstract
Hypoglycemic activity-guided fraction led to the isolation of the known compound, 4-hydroxybenzoic acid, from Pandanus odorus Ridl. (Thai name: Toei-hom, Pandanaceae). This compound showed a hypoglycemic effect in normal rats after the oral administration of 5 mg/kg. Additionally, the compound increased serum insulin levels and liver glycogen content in normal rats.
摘要
以降血糖活性为导向进行分离，从露兜树（泰国名：Toei-hom，露兜树科）中得到了已知化合物4-羟基苯甲酸。该化合物经口服给予正常大鼠5 mg/kg后显示出降血糖作用。此外，该化合物还提高了正常大鼠的血清胰岛素水平和肝糖原含量。
Zotero 插件