Gelwix T J, Beeson M S
Department of Emergency Medicine, Summa Health System, Akron, OH 44304, USA.
Am J Emerg Med. 1998 Sep;16(5):541-3. doi: 10.1016/s0735-6757(98)90015-8.
Skin necrosis is an uncommon complication of warfarin (Coumadin; Dupont Pharma, Wilmington, DE) therapy. The presentation may mimic other disorders. This article reports a case of a 72-year-old woman who presented to the emergency department complaining of swelling and ecchymosis to her left breast and right foot. The patient had been hospitalized for coronary artery bypass grafting, and had been discharged from the hospital earlier that day. This article reviews the pathophysiology and clinical features of warfarin-induced skin necrosis.
皮肤坏死是华法林（香豆素；杜邦制药公司，特拉华州威尔明顿）治疗中一种罕见的并发症。其表现可能与其他病症相似。本文报告了一例72岁女性病例，该患者因左乳房和右脚肿胀及瘀斑前往急诊科就诊。患者曾因冠状动脉搭桥术住院，并于当天早些时候出院。本文回顾了华法林所致皮肤坏死的病理生理学和临床特征。
