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耶兰杜尔研究:印度南部农村地区基于社区的癫痫研究——流行病学方面

The Yelandur study: a community-based approach to epilepsy in rural South India--epidemiological aspects.

作者信息

Mani K S, Rangan G, Srinivas H V, Kalyanasundaram S, Narendran S, Reddy A K

机构信息

Indian Epilepsy Association, Bangalore Chapter, India.

出版信息

Seizure. 1998 Aug;7(4):281-8. doi: 10.1016/s1059-1311(98)80019-8.

Abstract

Data on the epidemiology of epilepsy in a rural community in a developing country would be of value in planning a decentralized management of this malady in its early stages commensurate with available local resources. A detailed screening instrument covering various seizure types was used by trained paramedical workers in a door-to-door survey of a population of 64,963 in rural South India. The prevalence period was from 1 April 1990 to 31 March 1991. The crude prevalence rate per 1000 for active epilepsy was 4.38 for males, 3.40 for females and 3.91 for both. The minimum and maximum prevalence rates, the latter computed from a validation sample, were 3.91 and 4.63 for active epilepsy; 0.28 and 0.77 for inactive epilepsy and 4.19 and 5.41 for life-time prevalence. In addition, corresponding figures for hot-water epilepsy, a type of reflex epilepsy peculiar to this area, were 2.49 and 2.99 for active phase; 0.35 and 0.85 for inactive phase and 2.85 and 3.83 for life-time prevalence. The incidence rate for epilepsy was 49.3 per 100,000, the same as in developed countries. These data do not support the concept that the prevalence of epilepsy in developing countries is twice that in the developed world. However, the role of local/regional variations should be borne in mind before extrapolating the figures to an entire country.

摘要

关于发展中国家一个农村社区癫痫流行病学的数据,对于根据当地现有资源规划这种疾病早期的分散式管理具有重要价值。在印度南部农村对64963人进行的挨家挨户调查中,经过培训的辅助医务人员使用了一种涵盖各种癫痫发作类型的详细筛查工具。患病率调查期为1990年4月1日至1991年3月31日。活动性癫痫每1000人的粗患病率男性为4.38,女性为3.40,男女合计为3.91。活动性癫痫的最低和最高患病率(后者根据验证样本计算)分别为3.91和4.63;非活动性癫痫为0.28和0.77;终生患病率为4.19和5.41。此外,该地区特有的一种反射性癫痫——热水性癫痫的相应数据,活动期为2.49和2.99;非活动期为0.35和0.85;终生患病率为2.85和3.83。癫痫的发病率为每10万人49.3,与发达国家相同。这些数据并不支持发展中国家癫痫患病率是发达国家两倍的观点。然而,在将这些数据推广到整个国家之前,应考虑到当地/地区差异的作用。

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