Sciot R, Dal Cin P, Bellemans J, Samson I, Van den Berghe H, Van Damme B
Department of Pathology, University of Leuven, Belgium.
Virchows Arch. 1998 Aug;433(2):189-91. doi: 10.1007/s004280050235.
Synovial chondromatosis is a rare lesion, which is still believed by most authors to be reactive rather than neoplastic. We report on a case of synovial chondromatosis with clonal chromosomal changes [43,XX,der (1) t (1;13) (p21-22;q21),-6,-13,-14, add(21) (q21)]. The presence of clonal chromosomal changes in this and in three previously reported cases suggests that synovial chondromatosis is a true neoplastic lesion.
滑膜软骨瘤病是一种罕见的病变，大多数作者仍认为它是反应性的而非肿瘤性的。我们报告一例伴有克隆性染色体改变[43,XX,der(1)t(1;13)(p21 - 22;q21),-6,-13,-14,add(21)(q21)]的滑膜软骨瘤病。该病例以及之前报道的三例病例中存在克隆性染色体改变，提示滑膜软骨瘤病是一种真正的肿瘤性病变。
