Manthous C A, Schmidt G A, Hall J B
Pulmonary and Critical Care Division, Bridgeport Hospital and Yale University School of Medicine, Conn 06610, USA.
Chest. 1998 Sep;114(3):886-901. doi: 10.1378/chest.114.3.886.
Multiple complications associated with mechanical ventilation mandate that clinicians expeditiously define and reverse the pathophysiologic processes that precipitate respiratory failure and then, detect the earliest point that a patient can breathe without the ventilator. Over the past decade, numerous laboratory and clinical studies have been reported that may inform transformation of the "art of weaning" to the science of liberation. We review these studies and use them to formulate a systematic approach to assure early, safe, and successful liberation of patients from mechanical ventilation.
与机械通气相关的多种并发症要求临床医生迅速确定并扭转引发呼吸衰竭的病理生理过程，然后，检测出患者能够脱离呼吸机自主呼吸的最早时间点。在过去十年间，已有大量实验室和临床研究报告，这些研究可能有助于将“撤机技术”转变为撤机科学。我们回顾了这些研究，并以此制定出一种系统方法，以确保患者能够尽早、安全且成功地脱离机械通气。
