Levine J A, Morgan M Y
Endocrine Research Unit, Mayo Clinic, Rochester, MN 55905, USA.
Br J Cancer. 1998 Sep;78(5):579-81. doi: 10.1038/bjc.1998.543.
Indirect evidence suggests that cancer anorexia is associated with specific aversions to macronutrients. To investigate this, patients with cancer anorexia and hospitalized control subjects devised 3-day menus comprising foods that they wished to eat. These foods were then provided for 3 days and the intakes of each food carefully measured. As expected, patients with cancer anorexia consumed substantially less energy than hospitalized control subjects (6.0 +/- 0.9 MJ vs 9.5 +/- 0.5 MJ, P < 0.001). However, macronutrient composition was consistently maintained in the patients with cancer anorexia. These data argue against cancer anorexia representing a state of macronutrient aversion.
间接证据表明，癌症厌食症与对常量营养素的特定厌恶有关。为了对此进行研究，患有癌症厌食症的患者和住院对照受试者设计了一份包含他们想吃的食物的三日菜单。然后提供这些食物三天，并仔细测量每种食物的摄入量。正如预期的那样，患有癌症厌食症的患者摄入的能量明显低于住院对照受试者（6.0±0.9兆焦耳对9.5±0.5兆焦耳，P<0.001）。然而，癌症厌食症患者的常量营养素组成始终保持稳定。这些数据反驳了癌症厌食症代表常量营养素厌恶状态的观点。
