Ghayad E, Haddad F, el Aam C, Tohmé A, Nasr W
Service de Médecine interne, Hötel-Dieu de France, Beyrouth, Liban.
J Med Liban. 1997 Dec;45(4):191-6.
101 cases classified as inflammatory bowel disease at the Hôtel-Dieu de France Hospital between 1982 and 1994 were investigated. Files containing a sure diagnosis and complete clinical and biological investigations were included. 65 files were retained for the study: 48 cases had ulcerative colitis (UC), 17 had Crohn's disease (CD). UC averaged 4.7 admissions per 10,000 admissions to the hospital, while CD averaged 1.54 per 10,000. The UC/CD ratio was 2.8 and the Female/Male ratio was 1.4 for UC and 0.9 for CD. Medium follow-up was 6.4 years. 30% of our group was followed for more than 10 years. Overall frequency of extra-intestinal manifestations was similar to that reported worldwide. This is especially true for UC. However, no cases of ankylosing spondylitis, sclerosing cholangitis or erythema nodosum were found. One case of pyoderma gangrenosum was found in the series of CD. Extra-intestinal manifestations were found in 54% of UC patients and 94% of CD patients, probably because milder cases of this disease were misclassified as infectious diarrhea.
对1982年至1994年间在法国迪厄医院被归类为炎症性肠病的101例病例进行了调查。纳入了包含明确诊断以及完整临床和生物学检查的档案。研究保留了65份档案:48例患有溃疡性结肠炎(UC),17例患有克罗恩病(CD)。UC在该医院每10000例入院病例中平均有4.7例,而CD每10000例中平均有1.54例。UC与CD的比例为2.8,UC的女性/男性比例为1.4,CD为0.9。中位随访时间为6.4年。我们组中有30%的患者随访时间超过10年。肠外表现的总体发生率与全球报道的相似。UC尤其如此。然而,未发现强直性脊柱炎、硬化性胆管炎或结节性红斑病例。在CD系列中发现1例坏疽性脓皮病。54%的UC患者和94%的CD患者出现肠外表现,这可能是因为该疾病较轻的病例被误诊为感染性腹泻。