Vargas-Díez E, Feal-Cortizas C, Fraga J, Fernández-Herrera J, García-Díez A
Department of Dermatology, Hospital Universitario de la Princesa, Madrid, Spain.
Br J Dermatol. 1998 Jun;138(6):1075-8. doi: 10.1046/j.1365-2133.1998.02284.x.
We report a 73-year-old woman presenting with recurrent eruptions of generalized follicular pustules. Histological examination revealed several palisading necrobiotic granulomas with mucin deposits, with a perifollicular distribution. A dense neutrophilic infiltrate in the upper portion of affected follicular structures gave rise to pustulous lesions. Scaly papules and pseudovesiculous lesions over the palms with deeper necrobiotic granulomas involving sweat glands and epidermal perforation coexisted in some of the eruptions with generalized pustules. We propose the term follicular pustulous granuloma annulare for this peculiar form of granuloma annulare, which widens the clinicopathological spectrum of presentation of this disease.
我们报告了一位73岁女性，其出现全身性毛囊脓疱反复发作。组织学检查显示有多个伴有粘蛋白沉积的栅栏状坏死性肉芽肿，呈毛囊周围分布。受累毛囊结构上部密集的中性粒细胞浸润导致脓疱性病变。在一些伴有全身性脓疱的皮疹中，手掌上的鳞屑性丘疹和假水疱性病变与累及汗腺和表皮穿孔的深部坏死性肉芽肿并存。我们为此种特殊形式的环状肉芽肿提出“毛囊脓疱性环状肉芽肿”这一术语，它拓宽了该疾病临床表现的临床病理谱。
