中国洞庭湖地区日本血吸虫与乙型肝炎病毒感染之间不存在关联。
Absence of relationship between Schistosoma japonicum and hepatitis B virus infection in the Dongting lake region, China.
作者信息
Ye X P, Fu Y L, Anderson R M, Nokes D J
机构信息
The Wellcome Trust Centre for the Epidemiology of Infectious Disease, University of Oxford, UK.
出版信息
Epidemiol Infect. 1998 Aug;121(1):193-5. doi: 10.1017/s0950268898008917.
In order to determine whether infection with Schistosoma japonicum is related to a higher rate of infection with hepatitis B virus and/or to a higher probability of HBsAg chronic carriage, a population based survey was carried out in China in which HBV markers were studied in 112 subjects with long-lasting S. japonicum infection, and 93 subjects with no S. japonicum infection 37.5% of the cases and 40.9% of controls showed no markers of HBV infection. The prevalence rate of HBsAg was 12.5% in the cases and 12.9% in the controls. For anti-HBc and anti-HBs the figures were 59.8% and 59.8%, and 27.9% and 35.0%, respectively. These data do not support the hypothesis of an interaction between infection with hepatitis B virus and S. japonicum.
为了确定日本血吸虫感染是否与乙型肝炎病毒感染率较高和/或与HBsAg慢性携带的较高概率相关，在中国开展了一项基于人群的调查，对112例长期感染日本血吸虫的受试者和93例未感染日本血吸虫的受试者进行了HBV标志物研究。37.5%的病例和40.9%的对照未显示HBV感染标志物。病例组HBsAg患病率为12.5%，对照组为12.9%。抗-HBc和抗-HBs的数字分别为59.8%和59.8%，以及27.9%和35.0%。这些数据不支持乙型肝炎病毒感染与日本血吸虫感染之间存在相互作用的假设。
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