de Jong J C, Claas E C, Osterhaus A D
Nationaal Influenza Centrum van de WHO, Erasmus Universiteit, afd. Virologie, Rotterdam.
Ned Tijdschr Geneeskd. 1998 May 30;142(22):1252-6.
In 1997, 18 influenza patients were detected who were infected with influenza A(H5N1) virus. Six patients died. Presumably most of the patients had acquired the infection directly from chickens with the fowl plague prevalent in China in 1997. These are the first reported cases of isolation of influenza viruses belonging to one of the H4-H15 subtypes from human influenza patients. Man-to-man transmission of the virus has not been demonstrated but cannot be excluded in every case. Genetic analyses of seven of these virus isolates showed that no reassortment with a human or porcine influenza virus had occurred. It is unpredictable whether the H5N1-virus in question will start a pandemic in the next few years.
1997年，检测出18名感染甲型（H5N1）流感病毒的患者。6名患者死亡。据推测，大多数患者是直接从感染了1997年在中国流行的禽瘟的鸡身上感染的。这些是首次报道的从人类流感患者中分离出属于H4 - H15亚型之一的流感病毒的病例。该病毒的人际传播尚未得到证实，但在每种情况下都不能排除。对其中7株病毒分离株的基因分析表明，未发生与人类或猪流感病毒的重配。目前尚无法预测所讨论的H5N1病毒在未来几年是否会引发大流行。
