Jolliet P, Pichard C, Biolo G, Chioléro R, Grimble G, Leverve X, Nitenberg G, Novak I, Planas M, Preiser J C, Roth E, Schols A M, Wernerman J
Intensive Care Med. 1998 Aug;24(8):848-59. doi: 10.1007/s001340050677.
Severe protein-calorie malnutrition is a major problem in many intensive care (ICU) patients, due to the increased catabolic state often associated with acute severe illness and the frequent presence of prior chronic wasting conditions. Nutritional support is thus an important part of the management of these patients. Over the years, enteral nutrition (EN) has gained considerable popularity, due to its favorable effects on the digestive tract and its lower cost and rate of complications compared to parenteral nutrition. However, clinicians caring for ICU patients are often faced with contradictory data and difficult decisions when having to determine the optimal timing and modalities of EN administration, estimation of patient requirements, and choice of formulas. The purpose of this paper is to provide practical guidelines on these various aspects of enteral nutritional support, based on presently available evidence.
严重蛋白质 - 热量营养不良是许多重症监护病房(ICU)患者面临的主要问题,这是由于急性重症疾病常伴有分解代谢状态增加,以及先前慢性消瘦状况频繁出现。因此,营养支持是这些患者管理的重要组成部分。多年来,肠内营养(EN)因其对消化道的有利影响以及与肠外营养相比更低的成本和并发症发生率而广受欢迎。然而,在照顾ICU患者时,临床医生在确定肠内营养给药的最佳时机和方式、估计患者需求以及选择配方时,常常面临相互矛盾的数据和艰难的决策。本文旨在根据目前可得的证据,就肠内营养支持的这些不同方面提供实用指南。