Bernander R
Department of Microbiology, Biomedical Centre, Uppsala University, Sweden.
Mol Microbiol. 1998 Aug;29(4):955-61. doi: 10.1046/j.1365-2958.1998.00956.x.
Sequence similarity data suggest that archaeal chromosome replication is eukaryotic in character. Putative nucleoid-processing proteins display similarities to both eukaryotic and bacterial counterparts, whereas cell division may occur through a predominantly bacterial mechanism. Insights into the organization of the archaeal cell cycle are therefore of interest, not only for understanding archaeal biology, but also for investigating how components from the other two domains interact and work in concert within the same cell; in addition, archaea may have the potential to provide insights into eukaryotic initiation of chromosome replication.
序列相似性数据表明古细菌染色体复制具有真核生物的特征。假定的类核处理蛋白与真核生物和细菌的对应蛋白都有相似之处，而细胞分裂可能主要通过细菌机制发生。因此，深入了解古细菌细胞周期的组织不仅对于理解古细菌生物学很重要，而且对于研究来自其他两个域的成分如何在同一细胞内相互作用并协同工作也很重要；此外，古细菌可能有潜力为真核生物染色体复制的起始提供见解。
