Barton G M, Roath O S
Int J Vitam Nutr Res. 1976;46(3):271-4.
Leucocyte ascorbic acid was estimated in patients with abnormal leucocyte states and other haematological disorders. Levels below the normal range were found in most cases of chronic myeloid leukaemia and chronic lymphatic leukaemia. Subnormal levels were found in more than a third of patients with acute leukaemias, lymphomas, glandular fever, myelofibrosis, and polycythaemia, and in the same proportion of patients receiving cytotoxic drugs, and also in those with a polymorph leucocytosis and those with purpura. Most patients with anaemia but a normal leucocyte count, and those with myelomatosis had normal levels. The majority of pregnant women tested had subnormal levels. In a wide variety of leucocyte disorders the leucocyte ascorbic acid may not be an accurate index of the body's Vitamin C status. The results also support the supposition that leucocyte ascorbic acid is mostly carried by normal mature polymorphs.
对白细胞状态异常及其他血液系统疾病患者的白细胞中的维生素C含量进行了测定。在大多数慢性粒细胞白血病和慢性淋巴细胞白血病病例中，发现其含量低于正常范围。在超过三分之一的急性白血病、淋巴瘤、腺热、骨髓纤维化和红细胞增多症患者中，以及在接受细胞毒性药物治疗的相同比例患者中，还有那些有中性粒细胞增多症和紫癜的患者中，发现含量低于正常水平。大多数贫血但白细胞计数正常的患者以及患有骨髓瘤的患者，其含量正常。大多数接受检测的孕妇含量低于正常水平。在各种各样的白细胞疾病中，白细胞中的维生素C含量可能并非人体维生素C状态的准确指标。这些结果也支持了白细胞中的维生素C大多由正常成熟的中性粒细胞携带的推测。
