Boudray C, Grange C, Durieu I, Levrat R
Service de médecine interne, centre hospitalier Lyon-Sud, Pierre-Bénite, France.
Rev Med Interne. 1998 Jan;19(1):51-4. doi: 10.1016/s0248-8663(97)83700-9.
The occurrence of gastric carcinoid tumors during the cure of pernicious anemia has been reported in the literature. Concerning a new case, we review physiopathological data of this infrequent association.
We report the case of a 47-year-old women with pernicious anemia in which gastroscopy found two small tumors developed from enterochromaffin-like cells.
These tumors are usually latent and developed from enterochromaffin-like cells. The pathologic and histologic diagnosis is based on positive chromogranin A immunomarking. The physiopathological mechanism studies are in favour of the predominant part of hypergastrinemia following achlorhydria. Usually, evolution is benign and surgical or endoscopic resection recommended.