Lekovic V, Camargo P M, Klokkevold P R, Weinlaender M, Kenney E B, Dimitrijevic B, Nedic M
University of Belgrade, School of Dentistry, Faculty of Stomatology, Yugoslavia.
J Periodontol. 1998 Sep;69(9):1044-9. doi: 10.1902/jop.1998.69.9.1044.
The purpose of this study was to evaluate the clinical effectiveness of a bioabsorbable membrane made of glycolide and lactide polymers in preserving alveolar ridges following tooth extraction using a surgical technique based on the principles of guided bone regeneration. Sixteen patients requiring extractions of 2 anterior teeth or bicuspids participated in the study (split-mouth design). Following elevation of buccal and lingual full-thickness flaps and extraction of teeth, experimental sites were covered with bioabsorbable membranes; control sites did not receive any membrane. Titanium pins served as fixed reference points for measurements. Flaps were advanced in order to achieve primary closure of the surgical wound. No membrane became exposed in the course of healing. Reentry surgeries were performed at 6 months. Results showed that experimental sites presented with significantly less loss of alveolar bone height, more internal socket bone fill, and less horizontal resorption of the alveolar bone ridge. This study suggests that treatment of extraction sockets with membranes made of glycolide and lactide polymers is valuable in preserving alveolar bone in extraction sockets and preventing alveolar ridge defects.
本研究的目的是评估一种由乙交酯和丙交酯聚合物制成的生物可吸收膜,在基于引导骨再生原理的外科技术拔牙后保存牙槽嵴方面的临床效果。16名需要拔除2颗前牙或双尖牙的患者参与了本研究(采用双侧对照设计)。在掀起颊侧和舌侧全厚瓣并拔牙后,将实验部位用生物可吸收膜覆盖;对照部位未使用任何膜。钛钉作为测量的固定参考点。推进皮瓣以实现手术创口的一期闭合。在愈合过程中没有膜暴露。在6个月时进行再次手术。结果显示,实验部位的牙槽骨高度丧失明显较少,牙槽窝内骨填充较多,牙槽嵴的水平吸收较少。本研究表明,用乙交酯和丙交酯聚合物制成的膜处理拔牙窝,在保存拔牙窝内的牙槽骨和预防牙槽嵴缺损方面具有重要价值。