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衰老的C57BL小鼠群体的寿命、年龄变化及肿瘤发生率

Lifespan, age changes and tumour incidence in an ageing C57BL mouse colony.

作者信息

Rowlatt C, Chesterman F C, Sheriff M U

出版信息

Lab Anim. 1976 Oct;10(10):419-42. doi: 10.1258/002367776780956917.

DOI:10.1258/002367776780956917
PMID:979138
Abstract

Detailed data from a colony of C57BL mice kept for research into ageing processes are given on weights of 13 organs between the ages of 6 and 30 months; pathological findings and x-ray results from animals aged 6, 24 and 30 months; age-specific tumour incidences in 24 organs in 3-month period up to 36 months of age. Results of previously published age-related studies of reproductive capacity, dental abnormalities and brain changes are summarised.

摘要

给出了用于衰老过程研究的一群C57BL小鼠的详细数据,包括6至30月龄之间13个器官的重量;6、24和30月龄动物的病理检查结果和X光检查结果;直至36月龄的3个月时间段内24个器官的特定年龄肿瘤发病率。总结了先前发表的关于生殖能力、牙齿异常和大脑变化的年龄相关研究结果。

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