Quirós E, Piédrola G, Maroto M C
Department of Microbiology, Faculty of Medicine, University of Granada, Spain.
Eur J Epidemiol. 1998 Sep;14(6):617-9. doi: 10.1023/a:1007448501661.
GB virus C subtype (GBV-C) seems to share the same routes of transmission as other parenteral transmitted viruses. We have evaluated the prevalence of GBV-C in 247 patients with potential risk for GBV-C infection and in 91 healthy blood donors. The presence of GBV-C RNA was examined by polymerase chain reaction in serum samples. The 23.6% of parenteral drug users were GBV-C positive, 36.3% of them were also HIV infected. Moreover, 22.5 and 19% of sera from patients with HBV and HCV chronic hepatitis, respectively, but without apparent risk factors seemed GBV-C infected. Finally, the 6% of patients on hemodialysis were also positive. Therefore, these results suggest that GBV-C is transmitted by parenteral routes but other non-parenteral routes shared with HBV or HCV must be considered.
GB病毒C型（GBV-C）似乎与其他经肠道外传播的病毒具有相同的传播途径。我们评估了247名有GBV-C感染潜在风险的患者以及91名健康献血者中GBV-C的流行情况。通过聚合酶链反应检测血清样本中GBV-C RNA的存在情况。23.6%的肠道外药物使用者GBV-C呈阳性，其中36.3%也感染了HIV。此外，分别有22.5%和19%的慢性乙型肝炎和丙型肝炎患者血清似乎感染了GBV-C，但他们没有明显的风险因素。最后，6%的血液透析患者也呈阳性。因此，这些结果表明GBV-C通过肠道外途径传播，但必须考虑与乙型肝炎病毒或丙型肝炎病毒共有的其他非肠道外途径。
