Rosenblatt K A, Mathews W A, Daling J R, Voigt L F, Malone K
Department of Community Health, University of Illinois at Urbana-Champaign, Champaign 61820, USA.
Obstet Gynecol. 1998 Nov;92(5):753-6. doi: 10.1016/s0029-7844(98)00252-x.
To examine demographic and behavioral factors related to perineal application of powders.
Controls from three case-control studies (N = 1206) were asked identical questions about the use of genital powders by direct perineal application. The relationship of perineal powder application with demographic factors, reproductive factors, body mass index (BMI), douching, and alcohol and tobacco use was assessed. Data were analyzed by multiple logistic regression.
Women who douched (prevalence odds ratio [prevalence OR] 2.0, 95% confidence interval [CI] 1.0, 3.9), drank alcohol (prevalence OR 1.8, 95% CI 1.2, 2.8), smoked cigarettes (prevalence OR 1.3, 95% CI 1.0, 1.8), or were in the highest BMI quartile were more likely to engage in perineal use of powder (prevalence OR 1.6, 95% CI 1.1, 2.6). There appeared to be a close response relationship between the number of perineal applications of powder and BMI (P < .002).
Body mass index might confound the relationship between perineal powder application and the development of ovarian cancer. Other factors, such as alcohol and tobacco use and douching, are related to perineal use of powder and may represent similar behavioral characteristics.
研究与会阴部使用粉剂相关的人口统计学和行为因素。
对三项病例对照研究中的对照组（N = 1206）询问了关于直接会阴部使用生殖器粉剂的相同问题。评估了会阴部使用粉剂与人口统计学因素、生殖因素、体重指数（BMI）、灌洗以及饮酒和吸烟之间的关系。数据采用多因素逻辑回归分析。
进行灌洗的女性（患病率比值比[患病率OR] 2.0，95%置信区间[CI] 1.0，3.9）、饮酒的女性（患病率OR 1.8，95% CI 1.2，2.8）、吸烟的女性（患病率OR 1.3，95% CI 1.0，1.8）或BMI处于最高四分位数的女性更有可能会阴部使用粉剂（患病率OR 1.6，95% CI 1.1，2.6）。粉剂会阴部使用次数与BMI之间似乎存在密切的反应关系（P <.002）。
体重指数可能混淆会阴部使用粉剂与卵巢癌发生之间的关系。其他因素，如饮酒和吸烟以及灌洗，与会阴部使用粉剂有关，可能代表相似的行为特征。
