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1995年比利时出现的一起机场疟疾群发病例。

A cluster of airport malaria in Belgium in 1995.

作者信息

Van den Ende J, Lynen L, Elsen P, Colebunders R, Demey H, Depraetere K, De Schrijver K, Peetermans W E, Pereira de Almeida P, Vogelaers D

机构信息

Instituut voor Tropische Geneeskunde, Antwerpen.

出版信息

Acta Clin Belg. 1998 Aug;53(4):259-63. doi: 10.1080/17843286.1998.11772033.

DOI:10.1080/17843286.1998.11772033
PMID:9795446
Abstract

In Europe 64 cases of airport malaria have been registered between 1969 and 1996, most of them in France, Switzerland and Belgium. In the summer of 1995 six cases of airport malaria occurred at the International airport of Brussels, Belgium. Of the six patients three were airport employees, three were occasional visitors. One patient died, the diagnosis was made by PCR amplification and DNA sequencing after exhumation. Two different species of Plasmodium were detected, and infections occurred on at least two different floors of the airport. An inquiry revealed that the cabin of airplanes is correctly sprayed, according to WHO recommendations, but that the inside of the hand luggage, the cargo hold, the animal compartment, the wheel bays and container flights remain possible shelters for infected mosquitoes. In a case of fever of unknown origin, airport malaria should be considered in the differential diagnosis, especially during hot summers, and when thrombocytopenia is present. Additional antimosquito measures should be generalised, encompassing highly exposed personnel, container content and handling buildings, animal cages, wheel bays, and the boundary between the sorting and the reception of luggage.

摘要

1969年至1996年间,欧洲共记录了64例机场疟疾病例,其中大部分发生在法国、瑞士和比利时。1995年夏天,比利时布鲁塞尔国际机场发生了6例机场疟疾病例。6名患者中,3名是机场工作人员,3名是偶尔的访客。1名患者死亡,死后经PCR扩增和DNA测序确诊。检测到两种不同的疟原虫,感染发生在机场至少两层不同的区域。一项调查显示,根据世界卫生组织的建议,飞机客舱已正确喷洒杀虫剂,但手提行李内部、货舱、动物舱、轮舱和集装箱航班仍可能是受感染蚊子的藏身之处。对于不明原因发热的病例,在鉴别诊断时应考虑机场疟疾,尤其是在炎热的夏季以及出现血小板减少的情况下。应推广额外的防蚊措施,包括高暴露人群、集装箱内容物及处理建筑物、动物笼舍、轮舱以及行李分拣与接收区域之间的边界。

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