三种树脂类根管封闭剂的细胞毒性：一项体外评估
Cytotoxicity of three resin-based root canal sealers: an in vitro evaluation.
作者信息
Koulaouzidou E A, Papazisis K T, Beltes P, Geromichalos G D, Kortsaris A H
机构信息
Department of Endodontology, Dental School, Aristotle University, Thessaloniki, Greece.
出版信息
Endod Dent Traumatol. 1998 Aug;14(4):182-5. doi: 10.1111/j.1600-9657.1998.tb00834.x.
The cytotoxicity of three resin-based root canal sealers (AH26, AH-Plus, Topseal) was evaluated in vitro. The experiments included two cell lines, L929 mouse skin fibroblasts and RPC-C2A rat pulp cells. The cytotoxicity was assessed by sulforodamine B (SRB) colorimetric assay and hemocytometer viable cell counting after 24- and 48-h exposure. AH26 had a severe cytotoxic effect whilst Topseal and AH-Plus showed a markedly lower toxic influence on the cells during the experimental period.
体外评估了三种树脂基根管封闭剂（AH26、AH-Plus、Topseal）的细胞毒性。实验包括两种细胞系，L929小鼠皮肤成纤维细胞和RPC-C2A大鼠牙髓细胞。通过磺酰罗丹明B（SRB）比色法和血细胞计数器在暴露24小时和48小时后进行活细胞计数来评估细胞毒性。AH26具有严重的细胞毒性作用，而在实验期间Topseal和AH-Plus对细胞的毒性影响明显较低。
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