von Zumbusch A, Fiedler K, Mayerhofer A, Jessberger B, Ring J, Vogt H J
Department of Dermatology and Allergology, Technische Universität München, Germany.
Fertil Steril. 1998 Oct;70(4):643-6. doi: 10.1016/s0015-0282(98)00246-5.
To describe two cases in which intracytoplasmic sperm injection (ICSI) was successful for patients with infertility due to Kartagener's syndrome.
Case report.
Private hospital for gynecology department of reproductive medicine, and university hospital center for andrology.
PATIENT(S): Two couples with primary infertility due to Kartagener's syndrome in the male.
INTERVENTION(S): ICSI.
MAIN OUTCOME MEASURE(S): Pregnancy and birth after ICSI.
RESULT(S): In both couples, ICSI was successful in the first cycle. The uncomplicated pregnancies resulted in the birth of three healthy children. One female and male/female twins.
CONCLUSION(S): In couples with infertility due to Kartagener's syndrome in the male, ICSI has proved to be a successful therapy resulting in clinically healthy offspring. This knowledge may improve our understanding of the involvement of paternally inherited centrosomes, which nucleate microtubules, in human reproduction.
描述两例因卡塔格内综合征导致不孕的患者通过卵胞浆内单精子注射（ICSI）成功受孕的病例。
病例报告。
私立医院生殖医学妇科及大学医院男科中心。
两对夫妇，男方因卡塔格内综合征导致原发性不孕。
ICSI。
ICSI后的妊娠及分娩情况。
两对夫妇在第一个周期的ICSI均获成功。妊娠过程顺利，共诞下三名健康婴儿，其中包括一名女婴以及一对男/女双胞胎。
对于男方因卡塔格内综合征导致不孕的夫妇，ICSI已被证明是一种成功的治疗方法，能够诞下临床健康的后代。这一认识可能会增进我们对父系遗传的中心体（其为微管形成的核心）在人类生殖过程中所起作用的理解。
