de Graaf R A, Nicolay K
Department of Experimental In Vivo NMR, Image Sciences Institute and Bijvoet Center, Utrecht University, The Netherlands.
Magn Reson Med. 1998 Nov;40(5):690-6. doi: 10.1002/mrm.1910400508.
A new method for B1-insensitive water suppression using adiabatic RF pulses is described. The transition zone of the inversion profile of adiabatic full passage (AFP) pulses is used for frequency-selective excitation followed by dephasing of the excited water with magnetic field gradients. Several improvements of AFP pulses, which also have implications for other applications, are described. The technique was evaluated by simulations based on the Bloch equations (including relaxation), in vitro experiments and an in vivo verification on neonatal and adult rat brain.
描述了一种使用绝热射频脉冲进行B1不敏感水抑制的新方法。绝热全通（AFP）脉冲反转轮廓的过渡区用于频率选择性激发，随后通过磁场梯度使激发的水去相位。还描述了AFP脉冲的一些改进，这些改进对其他应用也有影响。该技术通过基于布洛赫方程（包括弛豫）的模拟、体外实验以及对新生大鼠和成年大鼠大脑的体内验证进行了评估。
