Vartiainen E, Pekkanen J, Koskinen S, Jousilahti P, Salomaa V, Puska P
Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland.
J Epidemiol Community Health. 1998 Jul;52(7):416-9. doi: 10.1136/jech.52.7.416.
To estimate the extent to which changes in blood pressure, smoking, and serum cholesterol concentration explain the observed increase in socioeconomic differences in mortality from ischaemic heart disease (IHD) in Finland during the past 20 years.
Predicted changes in mortality from IHD were calculated using logistic regression models with the risk factor levels assessed by cross sectional population surveys conducted in 1972, 1977, 1982, and 1987. The subjects included white collar and blue collar workers and farmers. The predicted changes were compared with the observed mortality changes in the same socioeconomic groups in the total population of the same geographical area.
North Karelia and Kuopio provinces, eastern Finland.
16,741 men and 16,389 women aged 30-59 randomly drawn from the population registers of the study areas. Mortality data were obtained from the total population in the same areas.
In men, the changes in diastolic blood pressure, total serum cholesterol, and smoking predicted a 28% decline in the mortality from IHD among white collar workers, a 30% decline among blue collar workers, and a 33% decline in farmers. Observed declines in the same socioeconomic groups were 61%, 40%, and 37%, respectively. In women, the predicted decline was 41% among white collar workers, 35% among blue collar workers, and 39% among farmers. The respective observed declines were 57%, 43%, and 20%.
Less than half of the decline in IHD mortality among white collar men was explained by the risk factor changes, while they explained 75% of the decline among blue collar men and 89% of the decline among male farmers. Changes in risk factors did not explain the increasing difference in IHD mortality between the socioeconomic groups, especially among men.
评估在过去20年中,血压、吸烟及血清胆固醇浓度的变化在多大程度上解释了芬兰缺血性心脏病(IHD)死亡率社会经济差异的增加。
使用逻辑回归模型计算IHD死亡率的预测变化,风险因素水平通过1972年、1977年、1982年和1987年进行的横断面人群调查评估。研究对象包括白领、蓝领工人和农民。将预测变化与同一地理区域总人口中相同社会经济群体的观察到的死亡率变化进行比较。
芬兰东部的北卡累利阿省和库奥皮奥省。
从研究区域的人口登记册中随机抽取16741名年龄在30 - 59岁的男性和16389名女性。死亡率数据来自同一地区的总人口。
在男性中,舒张压、总血清胆固醇和吸烟的变化预测白领工人中IHD死亡率下降28%,蓝领工人中下降30%,农民中下降33%。同一社会经济群体中观察到的下降分别为61%、40%和37%。在女性中,预测白领工人中下降41%,蓝领工人中下降35%,农民中下降39%。各自观察到的下降分别为57%、43%和20%。
白领男性中IHD死亡率下降的不到一半可由风险因素变化解释,而在蓝领男性中这一比例为75%,在男性农民中为89%。风险因素的变化并不能解释社会经济群体之间IHD死亡率日益增加的差异,尤其是在男性中。