Some examples of dose-response studies in chemical carcinogenesis.
作者信息
Port R, Schmähl D, Wahrendorf J
出版信息
Oncology. 1976;33(2):66-71. doi: 10.1159/000225107.
PMID:980371
Abstract
Three studies of DRUCKREY and his group, on diethylnitrosamine and 4-dimethylaminostilbene, are described. In a recent experiment, urethane was given chronically to rats and mice, at doses between 100 and 12,500 mug/kg/day. The results in rats were evaluated with the Mantel-Bryan procedure; risk estimates greatly differed, depending on the slope used for calculation.
摘要
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