Paganelli F, Amirat V, Ricard P, Trigano J A, Bues-Charbit M, Balansard G, Levy S
Service de Cardiologie, CHU Marseille Nord, Marseille.
Presse Med. 1998 Oct 10;27(30):1516-8.
Assess the efficacy of an anesthetic cream for cardiac catheterization.
Percutaneous anesthesia was studied in a series of 100 consecutive patients undergoing cardiac catheterization. The anesthesia was composed with an eutetic mixture of local anesthetics and applied precisely over the puncture area in a randomized controlled study. After admission, patients were randomized into two groups: 50 patients received lidocaine infiltration and 50 patients received associated cream and infiltration. Percutaneous anesthesia was to be applied 2 hours before entering the operating room.
No complication developed with this cream combined with lidocaine infiltration. Serum concentration indicated very low levels which were very well tolerated. Patient comfort improved with the anesthetic cream-lidocaine infiltration association.
The use of an anesthetic cream is safe and effective, especially combined with lidocaine infiltration during cardiac catheterization. Cost is high and the association might be reserved for special indications (obesity, children).
评估一种用于心脏导管插入术的麻醉乳膏的疗效。
对连续100例接受心脏导管插入术的患者进行了经皮麻醉研究。在一项随机对照研究中,麻醉剂由局部麻醉剂的共熔混合物组成,并精确地应用于穿刺区域。入院后,患者被随机分为两组:50例患者接受利多卡因浸润,50例患者接受联合乳膏及浸润。在进入手术室前2小时应用经皮麻醉。
该乳膏联合利多卡因浸润未出现并发症。血清浓度显示水平极低,耐受性良好。麻醉乳膏与利多卡因浸润联合使用可提高患者舒适度。
麻醉乳膏的使用安全有效,尤其是在心脏导管插入术期间与利多卡因浸润联合使用时。成本较高,这种联合使用可能仅适用于特殊情况(肥胖、儿童)。