Pfausler B, Vollert H, Bösch S, Schmutzhard E
Department of Neurology, Neurointensive Care Unit, University Hospital, Innsbruck, Austria.
J Travel Med. 1996 Sep 1;3(3):165-167. doi: 10.1111/j.1708-8305.1996.tb00732.x.
Cerebral venous thrombosis is a syndrome seen in association with a large number of disease processes. The commonest reported causes in adults are oral contraception,1 pregnancy and complications associated with the postpartum period,2 systemic malignancy,3 and infection.4 In approximately 20% of adult cases reported during the past 20 years no etiology was established.5 Cerebral venous thrombosis can be caused by similar mechanisms, such as venous thrombosis, occurring elsewhere in the body, e.g., blood vessel wall alterations attributable to inflammation, infection, or invasion of malignant cells, as well as from changes in blood flow due to dehydration and changes in the coagulability of the blood (e.g., from use of oral contraception). PC Gates and HJM Barnett list 38 causes of cerebral venous thrombosis that were proven by angiography or autopsy. One item on their list was dehydration/ hyperpyrexia.5 Recently thrombosis of the venae saphena or femoralis/iliaca has been reported to occur in long distance air travelers.6 We would like to report on five patients (out of 15) in whom cerebral venous thrombosis was causatively linked with either long distance air travel alone, air travel and diarrhea, or air travel and exposure to tropical heat.
脑静脉血栓形成是一种与大量疾病过程相关的综合征。成人中报道的最常见病因是口服避孕药、妊娠及产后期相关并发症、全身恶性肿瘤、感染。在过去20年报道的成人病例中，约20%未明确病因。脑静脉血栓形成可由类似机制引起，如身体其他部位发生的静脉血栓形成，例如由于炎症、感染或恶性细胞浸润导致的血管壁改变，以及由于脱水导致的血流变化和血液凝固性改变（如使用口服避孕药）。PC Gates和HJM Barnett列出了38种经血管造影或尸检证实的脑静脉血栓形成病因。他们列表中的一项是脱水/高热。最近有报道称长途航空旅行者会发生大隐静脉或股静脉/髂静脉血栓形成。我们想报告15例患者中的5例，其脑静脉血栓形成与单独的长途航空旅行、航空旅行与腹泻或航空旅行与热带高温暴露有因果关系。
