Weichselbaum R R, Epstein J, Little J B
Radiology. 1976 Nov;121(2):479-82. doi: 10.1148/121.2.479.
Four diploid cell strains were derived from skin biopsies from patients exhibiting unusually sensitive or resistant clinical responses to ionizing radiation during radiotherapy. The in vitro x-ray survival curve parameters for these strains were determined and compared with those of two normal human skin fibroblast strains. No systematic correlation could be demonstrated between these single dose survival parameters in vitro, and the clinical radiation response in vivo of the normal tissue or the tumor.
从放疗期间对电离辐射表现出异常敏感或抗性临床反应的患者皮肤活检中获得了四株二倍体细胞系。测定了这些细胞系的体外X射线存活曲线参数，并与两株正常人皮肤成纤维细胞系的参数进行了比较。在体外这些单剂量存活参数与体内正常组织或肿瘤的临床放射反应之间未发现系统性关联。
