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加拿大不列颠哥伦比亚省蜱传回归热:赫氏疏螺旋体的首次分离

Tick-borne relapsing fever in British Columbia, Canada: first isolation of Borrelia hermsii.

作者信息

Banerjee S N, Banerjee M, Fernando K, Burgdorfer W, Schwan T G

机构信息

B.C. Centre for Disease Control Society, Vector-Borne Diseases Laboratory, Vancouver, British Columbia V5Z 4R4, Canada.

出版信息

J Clin Microbiol. 1998 Dec;36(12):3505-8. doi: 10.1128/JCM.36.12.3505-3508.1998.

DOI:10.1128/JCM.36.12.3505-3508.1998
PMID:9817862
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC105229/
Abstract

The spirochete that causes tick-borne relapsing fever, Borrelia hermsii, was isolated in pure culture during 1995 and 1996 from three acutely ill human patients infected in southern British Columbia, Canada. The geographic area of exposure is a known focus of this disease dating back to 1930 when the first case was recognized in a human. Analyses of plasmid DNA, protein profiles, and reactivity with a species-specific monoclonal antibody identified the new isolates of spirochetes as B. hermsii, all of which were most similar to an isolate of this spirochete from northern California described previously. These are the first reported isolates of B. hermsii from Canada.

摘要

导致蜱传回归热的疏螺旋体——赫氏疏螺旋体(Borrelia hermsii),于1995年至1996年期间从加拿大不列颠哥伦比亚省南部感染的三名急性病患者中分离出纯培养物。暴露的地理区域是该疾病自1930年首例人类病例被确认以来的已知疫源地。对质粒DNA、蛋白质谱以及与种特异性单克隆抗体的反应性进行分析,确定新分离的疏螺旋体为赫氏疏螺旋体,所有这些分离株与先前描述的来自北加利福尼亚的该疏螺旋体分离株最为相似。这些是加拿大首次报道的赫氏疏螺旋体分离株。

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