Paumgartten F J, Delgado I F, Oliveira E S, Alleluia I B, Barretto H H, Kussumi T A
Laboratório de Toxicologia Ambiental, Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz. Av. Brasil 4365, Rio de Janeiro, RJ 21045-900, Brasil.
Cad Saude Publica. 1998;14 Suppl 3:33-9. doi: 10.1590/s0102-311x1998000700005.
Serum levels of organochlorine pesticides (OCP) were measured in agricultural workers from Rio de Janeiro State, Brazil. Blood samples from 26 volunteers (24 males, 02 females, 17-60 years old) were taken in October 1997. OCP residues (op'DDT pp'DDT, pp'DDD, pp'DDE, aldrin, dieldrin, endrin, heptachlor, heptachlor-epoxide, (alpha-, beta- and gamma-hexachlorocyclohexane, and hexachlorobenzene) were analyzed by gas chromatography with an electron capture detector. Tests detected pp'DDE in 16 out of 26 samples, but pp'DDE concentration exceeded 1.4 (microgram/L (i.e. 1.8, 2.4 and 4.4 microgram/L) in only 3 of these. beta-HCH was found in 6 (23.1%) out of 26 samples. In one sample (-HCH did not exceed 1.4 microgram/L, but in the remaining samples concentrations ranged from 1.4 to 5.3 microgram/L. The percentage of positive pp'DDE samples increased from the youngest </= 29 yrs: 30.0%) to the oldest age group ( >/= 40 yrs: 100%). A similar trend was found for beta-HCH contamination (</= 29 yrs: 0%; 30-39 yrs: 20.0%; >/= 40 yrs: 66.7%). Dieldrin was found in only one sample. No other OCP residue was found in the samples. Serum concentrations of OCPs found in this study are comparable to blood levels reported for the non-occupationally exposed population in Brazil and elsewhere.
对巴西里约热内卢州的农业工人血清中的有机氯农药（OCP）水平进行了测定。1997年10月采集了26名志愿者（24名男性，2名女性，年龄在17至60岁之间）的血样。采用带有电子捕获检测器的气相色谱法分析OCP残留（op'DDT、pp'DDT、pp'DDD、pp'DDE、艾氏剂、狄氏剂、异狄氏剂、七氯、环氧七氯、α-、β-和γ-六氯环己烷以及六氯苯）。检测发现26个样本中有16个含有pp'DDE，但其中只有3个样本的pp'DDE浓度超过1.4微克/升（即1.8、2.4和4.4微克/升）。26个样本中有6个（23.1%）检测出β-六氯环己烷。在一个样本中β-六氯环己烷未超过1.4微克/升，但在其余样本中浓度范围为1.4至5.3微克/升。pp'DDE阳性样本的百分比从最年轻的年龄组（≤29岁：30.0%）到最年长的年龄组（≥40岁：100%）呈上升趋势。β-六氯环己烷污染也发现了类似趋势（≤29岁：0%；30 - 39岁：20.0%；≥40岁：66.7%）。仅在一个样本中发现了狄氏剂。样本中未发现其他OCP残留。本研究中发现的OCP血清浓度与巴西及其他地区非职业暴露人群报告的血液水平相当。
