Organochlorine pesticide residues in human milk in Kayseri.

In this study: dichlorodiphenyltrichloroethane (DDT) and its metabolites [DDT + dichlorodiphenyl-dichloroethylene (DDE)], BHC (HCH) and their main isomers such as alpha, beta, gamma BHC, aldrin and its metabolite dieldrin, heptachloride, heptachloride epoxide, were investigated in 51 samples of breast milk of 51 lactating women during 1988. The ages of the mothers, who were working in agriculture, ranged from 17 to 33 y (mean 24.2 y). The concentrations of hexachlorobenzene (HCB), alpha BHC, beta BHC, gamma BHC, heptachloride, aldrin, heptachloride epoxide, pp'DDE, dieldrin, op'DDT, pp'DDT were found as 84 +/- 23, 96 +/- 20, 522 +/- 120, 156 +/- 20, 198 +/- 130, 47 +/- 9, 11 +/- 4, 2389 +/- 280, 6.7 +/- 3, 70 +/- 12, 410 +/- 60 micrograms kg-1 milk, fat, respectively, measured by gas chromatography (GC) method. The concentrations of chlorinated pesticides in human milk samples from Kayseri were compared with similar data obtained from other countries. The amounts of total BHC and aldrin derivatives were below the acceptable daily intake (ADI), whereas the amount of total DDT derivates was above, of the World Health Organization (WHO).