Bowie W R, Digiacomo R F, Holmes K K, Gale J L
Br J Vener Dis. 1978 Aug;54(4):235-8. doi: 10.1136/sti.54.4.235.
Inoculation of the urethra, conjunctiva, pharynx, and anal canal of six male crab-eating macaques (Macaca fascicularis) with urethral exudate from male patients with urethral gonorrhoea or with laboratory gonococcal strains was unsuccessful in establishing infection or producing increased polymorphonuclear leucocytes on Gram stain. Intraurethral inoculation with laboratory strains of Ureaplasma urealyticum resulted in transiently positive urethral cultures for U. urealyticum and was associated in some cases with increased numbers of polymorphonuclear leucocytes on Gram stain of urethral material. The findings suggest that the crab-eating macaque may be useful for studying the pathogenesis of urethral infection with U. urealyticum.
用男性尿道淋病患者的尿道渗出物或实验室淋病奈瑟菌菌株接种六只食蟹猕猴(食蟹猴)的尿道、结膜、咽部和肛管,未能成功建立感染或在革兰氏染色时产生更多的多形核白细胞。用解脲脲原体实验室菌株进行尿道内接种,导致解脲脲原体尿道培养物短暂呈阳性,在某些情况下,尿道材料革兰氏染色时多形核白细胞数量增加。这些发现表明,食蟹猕猴可能有助于研究解脲脲原体引起的尿道感染的发病机制。