Wheeler C B, Rodeheaver G T, Thacker J G, Edgerton M T, Edilich R F
Surg Gynecol Obstet. 1976 Nov;143(5):775-8.
This study was undertaken to identify side-effects of high pressure irrigation. Standardized surgical wounds made in Yorkshire pigs were subjected to high pressure syringe and pulsatile irrigation. As a result of these treatments, fluids were disseminated into the adjacent tissue of the wound, predominantly in a lateral direction. Bacteria did not accompany this disseminated fluid and apparently were filtered out by the surface tissues. This treatment results in a tissue injury which impairs its defenses, making the wound more susceptible to infection. However, the remarkable cleansing capacity of high pressure irrigation appears to outweigh this side-effect, since heavily contaminated wounds subjected to this treatment heal per primum without infection.
本研究旨在确定高压冲洗的副作用。在约克郡猪身上制造标准化手术伤口，然后对其进行高压注射器冲洗和脉动冲洗。这些处理的结果是，液体扩散到伤口的相邻组织中，主要是向侧面扩散。细菌并未随着这种扩散的液体一同扩散，显然被表层组织过滤掉了。这种处理会导致组织损伤，损害其防御能力，使伤口更容易受到感染。然而，高压冲洗显著的清洁能力似乎超过了这种副作用，因为接受这种处理的严重污染伤口一期愈合且未发生感染。
