Takada Y, Appert H E, Howard J M
Surg Gynecol Obstet. 1976 Nov;143(5):779-83.
Acute pancreatitis was produced in five dogs by injecting bile into the pancreatic duct. The capillary permeability effects of the exudate formed within the peritoneal cavity were studied by injecting the exudate intradermally into puppies. The amount of radioactively labeled albumin escaping from the circulation and appearing at the intradermal injection site was used as a measure of capillary permeability. It was observed that the peritoneal exudate, especially that produced in the early stage of bile induced pancreatitis, contains one or more substances which result in an increased capillary permeability when injected intradermally into puppies.
通过向五只狗的胰管注射胆汁来诱发急性胰腺炎。通过将腹腔内形成的渗出液皮内注射到幼犬体内，研究了该渗出液对毛细血管通透性的影响。从循环中逸出并出现在皮内注射部位的放射性标记白蛋白的量，被用作毛细血管通透性的衡量指标。观察到，腹腔渗出液，尤其是在胆汁诱导的胰腺炎早期产生的渗出液，含有一种或多种物质，当将其皮内注射到幼犬体内时，会导致毛细血管通透性增加。
