Liu K, Solomon N P, Luschei E S
Department of Speech Pathology and Audiology and the National Center for Voice and Speech, The University of Iowa, Iowa City 52242, USA.
Ann Otol Rhinol Laryngol. 1998 Nov;107(11 Pt 1):977-86. doi: 10.1177/000348949810701114.
Eliciting vocalization in anesthetized dogs by midbrain stimulation is a useful procedure for studies of laryngeal and respiratory physiology. The goal of this report has been to construct a canine stereotaxic "map" that would allow investigators to locate midbrain stimulus sites producing vocalization. Motor responses to electrical stimulation at currents of 1.5 mA or less were observed at 1,158 stimulus sites throughout the midbrains of 8 dogs. Vocalization was observed at 213 stimulus sites. The highest probability of observing vocalization was for sites located 6 to 10 mm anterior, 6 to 7 mm lateral, and 5 to 8 mm dorsal to earbar zero. The vocalization region most likely consists of axons arising in the midbrain periaqueductal gray and coursing through the adjacent tegmentum; low-threshold sites are close to the medial lemniscus. The relationship between stimulus sites at which vocalization was elicited and sites producing other motor responses is described.
通过中脑刺激诱发麻醉犬发声是研究喉和呼吸生理学的一种有用方法。本报告的目的是构建一个犬立体定位“图谱”，使研究人员能够定位产生发声的中脑刺激部位。在8只犬的整个中脑的1158个刺激部位观察到了对1.5 mA或更低电流的电刺激的运动反应。在213个刺激部位观察到了发声。观察到发声的最高概率是在耳杆零点前方6至10 mm、外侧6至7 mm和背侧5至8 mm处的部位。发声区域很可能由起源于中脑导水管周围灰质并穿过相邻被盖的轴突组成；低阈值部位靠近内侧丘系。描述了诱发发声的刺激部位与产生其他运动反应的部位之间的关系。
