64种药物在人体和大鼠体内口服剂量吸收分数的线性相关性。 - Suppr

Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats.

作者信息

Chiou W L, Barve A

机构信息

Department of Pharmaceutics and Pharmacodynamics (M/C 865) College of Pharmacy, University of Illinois at Chicago, 60612, USA.

出版信息

Pharm Res. 1998 Nov;15(11):1792-5. doi: 10.1023/a:1011981317451.

DOI:10.1023/a:1011981317451

PMID:9834005

Abstract

摘要

相似文献

Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats.

Pharm Res. 1998 Nov;15(11):1792-5. doi: 10.1023/a:1011981317451.

Evaluation of using dog as an animal model to study the fraction of oral dose absorbed of 43 drugs in humans.

Pharm Res. 2000 Feb;17(2):135-40. doi: 10.1023/a:1007552927404.

The validation of the intestinal permeability approach to predict oral fraction of dose absorbed in humans and rats.

Biopharm Drug Dispos. 1995 Jan;16(1):71-5. doi: 10.1002/bdd.2510160107.

Predicting human intestinal permeability using single-pass intestinal perfusion in rat.

J Pharm Pharm Sci. 2007;10(3):368-79.

Polar molecular surface properties predict the intestinal absorption of drugs in humans.

Pharm Res. 1997 May;14(5):568-71. doi: 10.1023/a:1012188625088.

[Pharmacokinetics of ipriflavone].

Acta Pharm Hung. 1995 Nov;65(6):219-22.

High-permeability criterion for BCS classification: segmental/pH dependent permeability considerations.

Mol Pharm. 2010 Oct 4;7(5):1827-34. doi: 10.1021/mp100175a. Epub 2010 Sep 3.

Pharmacokinetics of carbamazepine polymorphs and dihydrate in rats, related to dogs and humans.

Arch Pharm Res. 2011 Nov;34(11):1973-82. doi: 10.1007/s12272-011-1118-8. Epub 2011 Dec 3.

Exploring a Kinetic Model Approach in Biopharmaceutics: Estimating the Fraction Absorbed of Orally Administered Drugs in Humans.

J Pharm Sci. 2018 Jul;107(7):1798-1805. doi: 10.1016/j.xphs.2018.03.015. Epub 2018 Mar 21.

Estimation of the extent of oral absorption in animals from oral and intravenous pharmacokinetic data in drug discovery.

J Pharm Sci. 2009 Nov;98(11):4027-38. doi: 10.1002/jps.21705.

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Drug Deliv Transl Res. 2024 Nov;14(11):3309-3320. doi: 10.1007/s13346-024-01574-1. Epub 2024 Mar 25.

Prediction of Oral Drug Absorption in Rats from In Vitro Data.

Pharm Res. 2023 Feb;40(2):359-373. doi: 10.1007/s11095-022-03173-6. Epub 2022 Feb 15.

Characterization and Validation of a Chronic Model of Cyclophosphamide-Induced Interstitial Cystitis/Bladder Pain Syndrome in Rats.

Front Pharmacol. 2020 Aug 28;11:1305. doi: 10.3389/fphar.2020.01305. eCollection 2020.

LC478, a Novel Di-Substituted Adamantyl Derivative, Enhances the Oral Bioavailability of Docetaxel in Rats.

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Synergistic Effect of ZnO Nanoparticles and Carbon Nanotube and Polymeric Film on Electrochemical Oxidation of Acyclovir.

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Oral drug absorption in pediatrics: the intestinal wall, its developmental changes and current tools for predictions.

Biopharm Drug Dispos. 2017 Apr;38(3):209-230. doi: 10.1002/bdd.2052. Epub 2017 Feb 6.

Physiologically Based Absorption Modeling to Design Extended-Release Clinical Products for an Ester Prodrug.

AAPS J. 2016 Nov;18(6):1424-1438. doi: 10.1208/s12248-016-9950-x. Epub 2016 Jul 12.

Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination.

AAPS J. 2016 May;18(3):589-604. doi: 10.1208/s12248-016-9889-y. Epub 2016 Mar 10.

Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models.

Clin Pharmacokinet. 2016 Jun;55(6):673-96. doi: 10.1007/s40262-015-0351-6.

本文引用的文献

Caco-2 monolayers in experimental and theoretical predictions of drug transport.

Adv Drug Deliv Rev. 2001 Mar 1;46(1-3):27-43. doi: 10.1016/s0169-409x(00)00128-9.

Species differences in size discrimination in the paracellular pathway reflected by oral bioavailability of poly(ethylene glycol) and D-peptides.

J Pharm Sci. 1998 May;87(5):626-33. doi: 10.1021/js970120d.

Improved prediction of in vivo peroral absorption from in vitro intestinal permeability using an internal standard to control for intra- and inter-rat variability.

Pharm Res. 1997 Dec;14(12):1792-7. doi: 10.1023/a:1012148300807.

Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond.

Pharm Res. 1997 Dec;14(12):1655-8. doi: 10.1023/a:1012155124489.

Human intestinal permeability of piroxicam, propranolol, phenylalanine, and PEG 400 determined by jejunal perfusion.

Pharm Res. 1997 Sep;14(9):1127-32. doi: 10.1023/a:1012134219095.

New perspectives on the theory of permeability and resistance in the study of drug transport and absorption.

J Pharmacokinet Biopharm. 1996 Aug;24(4):433-42. doi: 10.1007/BF02353521.

Comparison between permeability coefficients in rat and human jejunum.

Pharm Res. 1996 Sep;13(9):1336-42. doi: 10.1023/a:1016065715308.

In vitro permeability through caco-2 cells is not quantitatively predictive of in vivo absorption for peptide-like drugs absorbed via the dipeptide transporter system.

Pharm Res. 1996 Jan;13(1):120-3. doi: 10.1023/a:1016045820933.

Measurements of the jejunal unstirred layer in normal subjects and patients with celiac disease.

Am J Physiol. 1996 Mar;270(3 Pt 1):G487-91. doi: 10.1152/ajpgi.1996.270.3.G487.

Determination of drug permeability in a flat or distended stirred intestine. Prediction of fraction dose absorbed in humans after oral administration.

Int J Clin Pharmacol Ther. 1994 Sep;32(9):474-82.

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Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats.

作者信息

Chiou W L, Barve A

机构信息

Department of Pharmaceutics and Pharmacodynamics (M/C 865) College of Pharmacy, University of Illinois at Chicago, 60612, USA.

出版信息

Pharm Res. 1998 Nov;15(11):1792-5. doi: 10.1023/a:1011981317451.

DOI:10.1023/a:1011981317451

PMID:9834005

Abstract

摘要

相似文献

Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats.

Pharm Res. 1998 Nov;15(11):1792-5. doi: 10.1023/a:1011981317451.

Evaluation of using dog as an animal model to study the fraction of oral dose absorbed of 43 drugs in humans.

Pharm Res. 2000 Feb;17(2):135-40. doi: 10.1023/a:1007552927404.

The validation of the intestinal permeability approach to predict oral fraction of dose absorbed in humans and rats.

Biopharm Drug Dispos. 1995 Jan;16(1):71-5. doi: 10.1002/bdd.2510160107.

Predicting human intestinal permeability using single-pass intestinal perfusion in rat.

J Pharm Pharm Sci. 2007;10(3):368-79.

Polar molecular surface properties predict the intestinal absorption of drugs in humans.

Pharm Res. 1997 May;14(5):568-71. doi: 10.1023/a:1012188625088.

[Pharmacokinetics of ipriflavone].

Acta Pharm Hung. 1995 Nov;65(6):219-22.

High-permeability criterion for BCS classification: segmental/pH dependent permeability considerations.

Mol Pharm. 2010 Oct 4;7(5):1827-34. doi: 10.1021/mp100175a. Epub 2010 Sep 3.

Pharmacokinetics of carbamazepine polymorphs and dihydrate in rats, related to dogs and humans.

Arch Pharm Res. 2011 Nov;34(11):1973-82. doi: 10.1007/s12272-011-1118-8. Epub 2011 Dec 3.

Exploring a Kinetic Model Approach in Biopharmaceutics: Estimating the Fraction Absorbed of Orally Administered Drugs in Humans.

J Pharm Sci. 2018 Jul;107(7):1798-1805. doi: 10.1016/j.xphs.2018.03.015. Epub 2018 Mar 21.

Estimation of the extent of oral absorption in animals from oral and intravenous pharmacokinetic data in drug discovery.

J Pharm Sci. 2009 Nov;98(11):4027-38. doi: 10.1002/jps.21705.

引用本文的文献

PBBM Considerations for Base Models, Model Validation, and Application Steps: Workshop Summary Report.

Mol Pharm. 2024 Nov 4;21(11):5353-5372. doi: 10.1021/acs.molpharmaceut.4c00758. Epub 2024 Sep 30.

Characterizing interregional differences in the rheological properties and composition of rat small intestinal mucus.

Drug Deliv Transl Res. 2024 Nov;14(11):3309-3320. doi: 10.1007/s13346-024-01574-1. Epub 2024 Mar 25.

Prediction of Oral Drug Absorption in Rats from In Vitro Data.

Pharm Res. 2023 Feb;40(2):359-373. doi: 10.1007/s11095-022-03173-6. Epub 2022 Feb 15.

Characterization and Validation of a Chronic Model of Cyclophosphamide-Induced Interstitial Cystitis/Bladder Pain Syndrome in Rats.

Front Pharmacol. 2020 Aug 28;11:1305. doi: 10.3389/fphar.2020.01305. eCollection 2020.

LC478, a Novel Di-Substituted Adamantyl Derivative, Enhances the Oral Bioavailability of Docetaxel in Rats.

Pharmaceutics. 2019 Mar 20;11(3):135. doi: 10.3390/pharmaceutics11030135.

Synergistic Effect of ZnO Nanoparticles and Carbon Nanotube and Polymeric Film on Electrochemical Oxidation of Acyclovir.

Iran J Pharm Res. 2018 Winter;17(1):52-62.

Oral drug absorption in pediatrics: the intestinal wall, its developmental changes and current tools for predictions.

Biopharm Drug Dispos. 2017 Apr;38(3):209-230. doi: 10.1002/bdd.2052. Epub 2017 Feb 6.

Physiologically Based Absorption Modeling to Design Extended-Release Clinical Products for an Ester Prodrug.

AAPS J. 2016 Nov;18(6):1424-1438. doi: 10.1208/s12248-016-9950-x. Epub 2016 Jul 12.

Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination.

AAPS J. 2016 May;18(3):589-604. doi: 10.1208/s12248-016-9889-y. Epub 2016 Mar 10.

Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models.

Clin Pharmacokinet. 2016 Jun;55(6):673-96. doi: 10.1007/s40262-015-0351-6.

本文引用的文献

Caco-2 monolayers in experimental and theoretical predictions of drug transport.

Adv Drug Deliv Rev. 2001 Mar 1;46(1-3):27-43. doi: 10.1016/s0169-409x(00)00128-9.

Species differences in size discrimination in the paracellular pathway reflected by oral bioavailability of poly(ethylene glycol) and D-peptides.

J Pharm Sci. 1998 May;87(5):626-33. doi: 10.1021/js970120d.

Improved prediction of in vivo peroral absorption from in vitro intestinal permeability using an internal standard to control for intra- and inter-rat variability.

Pharm Res. 1997 Dec;14(12):1792-7. doi: 10.1023/a:1012148300807.

Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond.

Pharm Res. 1997 Dec;14(12):1655-8. doi: 10.1023/a:1012155124489.

Human intestinal permeability of piroxicam, propranolol, phenylalanine, and PEG 400 determined by jejunal perfusion.

Pharm Res. 1997 Sep;14(9):1127-32. doi: 10.1023/a:1012134219095.

New perspectives on the theory of permeability and resistance in the study of drug transport and absorption.

J Pharmacokinet Biopharm. 1996 Aug;24(4):433-42. doi: 10.1007/BF02353521.

Comparison between permeability coefficients in rat and human jejunum.

Pharm Res. 1996 Sep;13(9):1336-42. doi: 10.1023/a:1016065715308.

In vitro permeability through caco-2 cells is not quantitatively predictive of in vivo absorption for peptide-like drugs absorbed via the dipeptide transporter system.

Pharm Res. 1996 Jan;13(1):120-3. doi: 10.1023/a:1016045820933.

Measurements of the jejunal unstirred layer in normal subjects and patients with celiac disease.

Am J Physiol. 1996 Mar;270(3 Pt 1):G487-91. doi: 10.1152/ajpgi.1996.270.3.G487.

Determination of drug permeability in a flat or distended stirred intestine. Prediction of fraction dose absorbed in humans after oral administration.

Int J Clin Pharmacol Ther. 1994 Sep;32(9):474-82.

Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats.

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Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats.

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