León C A
Acta Psiquiatr Psicol Am Lat. 1976 Sep;22(3):167-83.
This is a succint description of the International Pilot Study on Schizophrenia, sponsored by the World Health Organization and conducted in field research centers located in 9 different countries. The main objective of this study was the development of standard procedures for case finding, assessment of damage caused by Schizophrenia and observation of the course and outcome of the disorder. Starting in 1968, groups of approximately 120 patients who met the criteria both for inclusion and exclusion were studied in each center. They were subject to study by means of several instruments and were given a clinical diagnosis. On that basis, comparative analysis within and between centers were conducted, as well as reliability tests for the procedures used. Two follow-ups took place at 2 and 5 year intervals in order to obtain information about the course and outcome of cases. The emphasis of this presentation is placed on the findings at the Cali (Colombia) field reserach center and their comparison with the global results of centers in the rest of the world. In that context, the findings show that centers in developping countries are at least as capable for conducting research work as those in the developped countries. There is also the suggestion that mental disorders in developping countries apparently tend to more benign course and outcome.
这是对由世界卫生组织发起、在9个不同国家的实地研究中心开展的精神分裂症国际试点研究的简要描述。这项研究的主要目标是制定用于病例发现、评估精神分裂症所致损害以及观察该疾病病程和转归的标准程序。从1968年开始,每个中心对约120名符合纳入和排除标准的患者进行研究。他们接受了多种手段的研究并得到了临床诊断。在此基础上,进行了中心内部和中心之间的比较分析以及所用程序的可靠性测试。每隔2年和5年进行两次随访,以获取有关病例病程和转归的信息。本报告重点介绍了位于卡利(哥伦比亚)的实地研究中心的研究结果及其与世界其他地区中心的总体结果的比较。在这方面,研究结果表明,发展中国家的中心至少与发达国家的中心一样有能力开展研究工作。还有迹象表明,发展中国家的精神障碍显然往往有更良性的病程和转归。