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一种用于人体皮肤和肺部激发实验的新型全身暴露舱——小麦粉气溶胶的产生

A new whole-body exposure chamber for human skin and lung challenge experiments--the generation of wheat flour aerosols.

作者信息

Lidén C, Lundgren L, Skare L, Lidén G, Tornling G, Krantz S

机构信息

Department of Occupational and Environmental Dermatology, Karolinska Hospital, Stockholm, Sweden.

出版信息

Ann Occup Hyg. 1998 Nov;42(8):541-7.

PMID:9838867
Abstract

A new whole-body exposure chamber for human skin and lung challenge offers possibilities for experimental exposure challenges carried out in clinical practice, for exposure of patients, in research and for investigations of the effects of exposure on the skin and in the respiratory tract. The chamber system can be used for both aerosols and gases. Dynamically controlled, the chamber is relatively easy to operate and to clean. Air exchange rates can be varied between 6-12/h. Initial studies with wheat flour have been carried out. The homogeneity and stability of the wheat flour aerosol concentration (the spatial and the temporal variation) inside the chamber can be kept at acceptable levels.

摘要

一种用于人体皮肤和肺部激发试验的新型全身暴露舱,为临床实践中进行的实验性暴露激发试验、患者暴露、研究以及暴露对皮肤和呼吸道影响的调查提供了可能性。该舱体系统可用于气溶胶和气体。该舱体动态可控,操作和清洁相对容易。空气交换率可在6 - 12次/小时之间变化。已经开展了用小麦粉进行的初步研究。舱内小麦粉气溶胶浓度的均匀性和稳定性(空间和时间变化)可保持在可接受水平。

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