Baran-Raunstrup K, Miedzobrodzki J, Ternowitz T
Department of Dermatology, Marselisborg Hospital, University of Aarhus, Denmark.
Acta Microbiol Pol. 1998;47(2):167-75.
Staphylococcus aureus strains from atopic dermatitis (AD) patients were investigated. Diversities of biological properties, strain relationships and/or group tendencies between strains were analysed. Fifty four S. aureus strains were divided into seven biotypes using a standard biochemical API Staph system. The largest population (twenty two isolates, 40.7%) belonged to biotype A No. 6716153. Using a standard phage set S. aureus isolates were typed into three groups: I, II and III. However, twenty seven (50.0%) isolates belonged to group No. III. Production of proteolytic enzymes was expressed by all isolates, and 87.0% showed high or moderate proteolytic activity. Also alpha or beta haemolysins production by 83.0% of the strains was demonstrated. Antimicrobial susceptibility for each strain was analysed using fifteen antibiotics. Most isolates were sensitive to chloramphenicol (98.0%), neomycin (98.0%) and fucidin (88.0%) and were resistant to ampicillin, oxacillin and rondomycin (< 20.0%). No isolate was sensitive to all antibiotics of our study. Obvious correlations were not observed between biochemical types, phage types, haeomolysin production and antibiotic resistance pattern but proteolytic activity was demonstrated by most strains in each test.
对来自特应性皮炎（AD）患者的金黄色葡萄球菌菌株进行了研究。分析了菌株之间生物学特性的多样性、菌株关系和/或群体倾向。使用标准生化API葡萄球菌系统将54株金黄色葡萄球菌菌株分为7种生物型。最大的群体（22株分离株，40.7%）属于生物型A第6716153号。使用标准噬菌体组将金黄色葡萄球菌分离株分为三组：I、II和III。然而，27株（50.0%）分离株属于III组。所有分离株均表现出蛋白水解酶的产生，87.0%表现出高或中度蛋白水解活性。此外，83.0%的菌株产生α或β溶血素。使用15种抗生素分析了每种菌株的抗菌敏感性。大多数分离株对氯霉素（98.0%）、新霉素（98.0%）和夫西地酸（88.0%）敏感，对氨苄西林、苯唑西林和林可霉素耐药（<20.0%）。我们研究中的分离株对所有抗生素均不敏感。在生化类型、噬菌体类型、溶血素产生和抗生素耐药模式之间未观察到明显的相关性，但在每项试验中大多数菌株都表现出蛋白水解活性。
