Nebel O T, Fornes M F, Castell D O
Am J Dig Dis. 1976 Nov;21(11):953-6. doi: 10.1007/BF01071906.
The incidence and precipitating factors associated with symptomatic gastroesophageal reflux were evaluated by a questionnaire in 446 hospitalized and 558 nonhospitalized subjects. Of 385 control subjects 7% experienced heartburn daily, 14% noted heartburn weekly, and 15% experienced it once a month, giving a total of 36% of subjects having heartburn at least monthly. Daily heartburn occurred at a significantly greater (P less than 0.05) rate for 246 medical inpatients (14%) and for 121 patients seen in outpatient gastroenterological clinic (15%). Pregnant women seen in uncomplicated obstetrical clinic had symptoms of significantly greater (P less than 0.01) incidence: daily (25%) and at least once monthly (52%). Age, sex, or hospitalization did not significantly affect incidence. Fried foods, "spicy" foods, and alcohol were the most common precipitating factors.
通过问卷调查评估了446名住院患者和558名非住院患者中与症状性胃食管反流相关的发病率及诱发因素。在385名对照受试者中，7%的人每天出现烧心症状，14%的人每周出现烧心症状，15%的人每月出现一次烧心症状，总计36%的受试者至少每月出现一次烧心症状。246名内科住院患者（14%）和121名门诊胃肠病诊所患者（15%）每天出现烧心症状的比例显著更高（P<0.05）。在未合并并发症的产科诊所就诊的孕妇出现症状的比例显著更高（P<0.01）：每天（25%）和至少每月一次（52%）。年龄、性别或是否住院对发病率没有显著影响。油炸食品、“辛辣”食品和酒精是最常见的诱发因素。
