Lee M G, Jeong Y K, Kim M H, Lee S G, Kang E M, Chien D, Shin Y M, Ha H K, Kim P N, Auh Y H
Department of Diagnostic Radiology, University of Ulsan Asan Medical Center, Seoul, Korea.
AJR Am J Roentgenol. 1998 Dec;171(6):1539-45. doi: 10.2214/ajr.171.6.9843285.
In this study, we compared the single-shot rapid acquisition with relaxation enhancement (RARE) sequence with the multislice half-Fourier acquisition single-shot turbo spin-echo (HASTE) sequence to assess the ability of each technique to show various pancreaticobiliary diseases using MR cholangiopancreatography.
MR cholangiopancreatography was performed using both the single-shot RARE and the multislice HASTE pulse sequences in 80 consecutive subjects in whom we had proof of a range of diagnoses. The study population included healthy subjects (n = 9), patients with benign lesions (n = 41), and patients with malignant lesions (n = 30). We analyzed each image using the following criteria: the cause of the lesions, the image quality (i.e., the amount of artifact and the sharpness of anatomic structures such as the right and left hepatic ducts, the extrahepatic bile duct, and the main pancreatic duct), and the reviewers' preference of images. The images were evaluated independently by two radiologists who were unaware of the results of the other cholangiopancreatographic sequence and of the diagnosis.
Artifacts were less prominent in images that were obtained using the single-shot RARE sequence (p = .0192); however, the sharpness of anatomic structures was the same using either sequence (p = .1673). For images that were obtained using the single-shot RARE technique, the sensitivity, specificity, and accuracy in distinguishing malignant from other abnormalities were 83%, 78%, and 80%, respectively; for the multislice HASTE technique, these values were 77%, 72%, and 74%, respectively (p > .05). Disease-specific accuracy in determining the correct diagnosis was 54% and 59%, respectively (p > .05). In patients in whom all the ducts needed to be defined, the single-shot RARE technique was preferred to the multislice HASTE technique (p < .01).
The single-shot RARE technique shows fewer artifacts and is preferred to the multislice HASTE technique. However, both techniques show the same degree of sharpness of anatomic structures, both are able to reveal malignant diseases, and both provide enough information to determine a specific diagnosis.
在本研究中，我们将单次激发快速采集与弛豫增强（RARE）序列与多层半傅里叶采集单次激发快速自旋回波（HASTE）序列进行比较，以评估每种技术在磁共振胰胆管造影中显示各种胰胆管疾病的能力。
在80例连续的受试者中，使用单次激发RARE和多层HASTE脉冲序列进行磁共振胰胆管造影，这些受试者具有一系列确诊依据。研究人群包括健康受试者（n = 9）、良性病变患者（n = 41）和恶性病变患者（n = 30）。我们使用以下标准分析每张图像：病变原因、图像质量（即伪影量以及左右肝管、肝外胆管和主胰管等解剖结构的清晰度）以及阅片者对图像的偏好。图像由两名放射科医生独立评估，他们不知道另一种胰胆管造影序列的结果以及诊断情况。
使用单次激发RARE序列获得的图像中伪影不那么明显（p = .0192）；然而，两种序列获得的解剖结构清晰度相同（p = .1673）。对于使用单次激发RARE技术获得的图像，区分恶性病变与其他异常的敏感性、特异性和准确性分别为83%、78%和80%；对于多层HASTE技术，这些值分别为77%、72%和74%（p > .05）。确定正确诊断的疾病特异性准确性分别为54%和59%（p > .05）。在所有导管都需要明确显示的患者中，单次激发RARE技术比多层HASTE技术更受青睐（p < .01）。
单次激发RARE技术显示的伪影较少，比多层HASTE技术更受青睐。然而，两种技术显示的解剖结构清晰度程度相同，都能够揭示恶性疾病，并且都提供了足够的信息来确定具体诊断。
