Gerber J, Tumani H, Kolenda H, Nau R
Department of Neurology, University of Göttingen, Germany.
Neurology. 1998 Dec;51(6):1710-4. doi: 10.1212/wnl.51.6.1710.
Protein concentration, leukocyte density, and lactate concentration were studied in 41 pairs of ventricular and lumbar CSF drawn at an interval of less than 24 hours from patients with suspected bacterial CNS infections. The ventriculo-lumbar ratios ranged from 0.003 to 10.2 (median=0.42) for protein and from 0.002 to 53.5 (median=0.17) for leukocytes. The uneven distribution of leukocytes and proteins in the CSF space may produce findings that fail to indicate bacterial CNS infections. Lactate was distributed more homogeneously in the CSF space than protein and leukocytes (ventriculo-lumbar ratio 0.52 to 1.66 [median=0.811).
对41例疑似细菌性中枢神经系统感染患者在间隔不到24小时内采集的41对脑室和腰椎脑脊液样本进行了蛋白质浓度、白细胞密度和乳酸浓度研究。蛋白质的脑室-腰椎比值范围为0.003至10.2（中位数=0.42），白细胞的比值范围为0.002至53.5（中位数=0.17）。脑脊液空间中白细胞和蛋白质的分布不均可能导致无法提示细菌性中枢神经系统感染的结果。与蛋白质和白细胞相比，乳酸在脑脊液空间中的分布更均匀（脑室-腰椎比值为0.52至1.66[中位数=0.81]）。
