Howard C J, Taylor G, Collins J, Gourlay R N
Infect Immun. 1976 Jul;14(1):11-7. doi: 10.1128/iai.14.1.11-17.1976.
Mycoplasma dispar and Mycoplasma agalactiae subsp. bovis survived or grew in cultures of bovine lacteal polymorphonuclear leukocytes or bovine alveolar macrophages. In the presence of specific bovine antibody, macrophages and polymorphonuclear leukocytes appeared to kill both species of mycoplasma. Specific rabbit antisera also promoted the killing of these mycoplasmas by bovine macrophages but had no demonstrable activity for bovine polymorphonuclear leukocytes. It is suggested that phagocytosis of these mycoplasmas by bovine cells occurs only in the presence of specific antibody. The experiments also indicate that differences exist between bovine polymorphonuclear leukocytes and macrophages with regard to their receptor sites for immunoglobulins.
殊异支原体和无乳支原体牛亚种可在牛乳腺多形核白细胞或牛肺泡巨噬细胞培养物中存活或生长。在特异性牛抗体存在的情况下,巨噬细胞和多形核白细胞似乎可杀死这两种支原体。特异性兔抗血清也可促进牛巨噬细胞对这些支原体的杀伤,但对牛多形核白细胞无明显活性。提示牛细胞对这些支原体的吞噬作用仅在特异性抗体存在时发生。实验还表明,牛多形核白细胞和巨噬细胞在免疫球蛋白受体位点方面存在差异。