Mackiewicz B
Clinic of Lung Diseases, Medical Academy, Jaczewskiego 8, 20-090 Lublin, Poland.
Ann Agric Environ Med. 1998;5(2):169-75.
Occupational inhalation of organic dust may be a cause of numerous symptoms and diseases. Organic dust consists of various biological compounds which induce inflammatory reactions in the lungs on an immunotoxic or allergic basis. Bacteria and their metabolites, moulds and their spores, mycotoxins, glucans, and other still unidentified substances, can be potential aetiologic factors of diseases caused by organic dust. The aim of this study was to determine the concentration and composition of airborne microflora in typical Polish swine buildings and to assess the health conditions of the workers employed within them. Total concentration of microorganisms in the air of five examined swine breeding farms ranged from 613.7-1246.7 x 10(3) cfu/m3 (mean value 930.6 x 10(3) cfu/ m3). The examination of 53 employees working in the swine buildings included their medical history, physical examination, spirometry, and allergological tests. Work-related symptoms were reported by 31 (58.5%) of the subjects. No abnormal findings were present upon physical and spirometric examinations. The results suggest the common occurrence of work-related respiratory disease in swine workers, mostly corresponding to the Organic Dust Toxic Syndrome (ODTS).
职业性吸入有机粉尘可能是多种症状和疾病的病因。有机粉尘由各种生物化合物组成，这些化合物在免疫毒性或过敏的基础上引发肺部炎症反应。细菌及其代谢产物、霉菌及其孢子、霉菌毒素、葡聚糖和其他尚未确定的物质，可能是有机粉尘所致疾病的潜在病因。本研究的目的是确定波兰典型猪场空气中微生物群落的浓度和组成，并评估场内工作人员的健康状况。在所检测的五个猪场中，空气中微生物的总浓度范围为613.7 - 1246.7×10³ cfu/m³（平均值为930.6×10³ cfu/m³）。对53名在猪场工作的员工进行的检查包括病史询问、体格检查、肺活量测定和过敏测试。31名（58.5%）受试者报告了与工作相关的症状。体格检查和肺活量测定均未发现异常结果。结果表明，猪场工人中与工作相关的呼吸道疾病普遍存在，大多符合有机粉尘毒性综合征（ODTS）。
