• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Intestinal IgA: novel views on its function in the defence of the largest mucosal surface.肠道IgA:关于其在保护最大黏膜表面中功能的新观点。
Gut. 1999 Jan;44(1):2-5. doi: 10.1136/gut.44.1.2.
2
Intestinal IgA synthesis: regulation of front-line body defences.肠道IgA合成:一线身体防御的调节
Nat Rev Immunol. 2003 Jan;3(1):63-72. doi: 10.1038/nri982.
3
Structural insights into antibody-mediated mucosal immunity.抗体介导的黏膜免疫的结构见解。
Curr Top Microbiol Immunol. 2006;308:173-204. doi: 10.1007/3-540-30657-9_8.
4
Regional specialization in the mucosal immune system: what happens in the microcompartments?黏膜免疫系统中的区域特化:微区室中发生了什么?
Immunol Today. 1999 Mar;20(3):141-51. doi: 10.1016/s0167-5699(98)01413-3.
5
[IgA, an essential part of the immune system: selected issues].[免疫球蛋白A,免疫系统的重要组成部分:若干选定问题]
Postepy Hig Med Dosw (Online). 2007 Jan 29;61:38-47.
6
T cell and cytokine regulation of the IgA response.T细胞与细胞因子对IgA应答的调节
Chem Immunol. 1998;71:209-34. doi: 10.1159/000058712.
7
Evolution, development, mechanism and function of IgA in the gut.肠道中IgA的进化、发育、机制及功能
Curr Opin Immunol. 2008 Apr;20(2):170-7. doi: 10.1016/j.coi.2008.04.002. Epub 2008 May 2.
8
Parenteral nutrition impairs gut-associated lymphoid tissue and mucosal immunity by reducing lymphotoxin Beta receptor expression.肠外营养通过降低淋巴毒素β受体表达来损害肠道相关淋巴组织和黏膜免疫。
Ann Surg. 2006 Sep;244(3):392-9. doi: 10.1097/01.sla.0000234797.42935.46.
9
Peyer's patch dendritic cells as regulators of mucosal adaptive immunity.派尔集合淋巴结树突状细胞作为黏膜适应性免疫的调节因子。
Cell Mol Life Sci. 2005 Jun;62(12):1333-8. doi: 10.1007/s00018-005-5037-z.
10
GALT: organization and dynamics leading to IgA synthesis.GALT:导致 IgA 合成的组织和动态。
Adv Immunol. 2010;107:153-85. doi: 10.1016/B978-0-12-381300-8.00006-X.

引用本文的文献

1
Polymeric immunoglobulin receptor (pIgR) in cancer progression: a critical role and potential therapeutic target.聚合免疫球蛋白受体(pIgR)在癌症进展中的关键作用及潜在治疗靶点
Apoptosis. 2025 May 26. doi: 10.1007/s10495-025-02116-x.
2
Mucosal immune responses to SARS-CoV-2 infection and COVID-19 vaccination.对严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染和2019冠状病毒病(COVID-19)疫苗接种的黏膜免疫反应
Vaccine. 2025 May 22;56:127175. doi: 10.1016/j.vaccine.2025.127175. Epub 2025 Apr 30.
3
Induction of Immune Responses in Mice and Newborn Piglets by Oral Immunization with Recombinant Expressing S1 and M Proteins of Porcine Epidemic Diarrhea Virus.用表达猪流行性腹泻病毒S1和M蛋白的重组体经口免疫小鼠和新生仔猪诱导免疫反应
Microorganisms. 2025 Mar 21;13(4):714. doi: 10.3390/microorganisms13040714.
4
Loss of GalNAc-T14 links O-glycosylation defects to alterations in B cell homing in IgA nephropathy.GalNAc-T14的缺失将O-糖基化缺陷与IgA肾病中B细胞归巢的改变联系起来。
J Clin Invest. 2025 Mar 18;135(10). doi: 10.1172/JCI181164. eCollection 2025 May 15.
5
Supramolecular Peptide Self-Assemblies Facilitate Oral Immunization.超分子肽自组装促进口服免疫。
ACS Biomater Sci Eng. 2024 May 13;10(5):3041-3056. doi: 10.1021/acsbiomaterials.4c00525. Epub 2024 Apr 16.
6
Recombinant neutralizing secretory IgA antibodies for preventing mucosal acquisition and transmission of SARS-CoV-2.用于预防 SARS-CoV-2 黏膜获得和传播的重组中和分泌型 IgA 抗体。
Mol Ther. 2024 Mar 6;32(3):689-703. doi: 10.1016/j.ymthe.2024.01.025. Epub 2024 Jan 24.
7
Effects of Dietary Ferulic Acid on Intestinal Health and Ileal Microbiota of Tianfu Broilers Challenged with Lipopolysaccharide.饲粮阿魏酸对脂多糖攻毒天府肉鸡肠道健康和回肠微生物区系的影响。
Molecules. 2023 Feb 10;28(4):1720. doi: 10.3390/molecules28041720.
8
Teleost swim bladder, an ancient air-filled organ that elicits mucosal immune responses.硬骨鱼的鳔是一种古老的充满空气的器官,可引发黏膜免疫反应。
Cell Discov. 2022 Apr 5;8(1):31. doi: 10.1038/s41421-022-00393-3.
9
Corrigendum: Inflammatory and Microbiota-Related Regulation of the Intestinal Epithelial Barrier.勘误:肠道上皮屏障的炎症与微生物群相关调节
Front Nutr. 2021 Nov 1;8:790387. doi: 10.3389/fnut.2021.790387. eCollection 2021.
10
Inflammatory and Microbiota-Related Regulation of the Intestinal Epithelial Barrier.肠道上皮屏障的炎症与微生物群相关调节
Front Nutr. 2021 Sep 13;8:718356. doi: 10.3389/fnut.2021.718356. eCollection 2021.

本文引用的文献

1
In vitro comparison of the biologic activities of monoclonal monomeric IgA, polymeric IgA, and secretory IgA.单克隆单体IgA、多聚IgA和分泌型IgA生物活性的体外比较
J Immunol. 1998 Feb 1;160(3):1219-23.
2
A mucosal intranet: intestinal epithelial cells down-regulate intraepithelial, but not peripheral, T lymphocytes.黏膜内网:肠上皮细胞下调上皮内而非外周T淋巴细胞。
J Immunol. 1998 Mar 1;160(5):2188-96.
3
Physical and functional association of Fc alpha R with protein tyrosine kinase Lyn.FcαR与蛋白酪氨酸激酶Lyn的物理和功能关联。
Blood. 1998 Jan 15;91(2):383-91.
4
Natural polyreactive secretory immunoglobulin A autoantibodies as a possible barrier to infection in humans.天然多反应性分泌型免疫球蛋白A自身抗体可能是人类感染的一道屏障。
Infect Immun. 1997 Oct;65(10):3997-4004. doi: 10.1128/iai.65.10.3997-4004.1997.
5
Infection of gastrointestinal tract macrophages by HIV-1.HIV-1对胃肠道巨噬细胞的感染。
J Leukoc Biol. 1997 Jul;62(1):72-7. doi: 10.1002/jlb.62.1.72.
6
IgA antibody as a non-inflammatory regulator of immunity.IgA抗体作为免疫的非炎症调节因子。
Biochem Soc Trans. 1997 May;25(2):466-70. doi: 10.1042/bst0250466.
7
Production of secretory immunoglobulin A by a single mammalian cell.单个哺乳动物细胞分泌免疫球蛋白A的产生。
Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6364-8. doi: 10.1073/pnas.94.12.6364.
8
On the front lines: intraepithelial lymphocytes as primary effectors of intestinal immunity.前沿:上皮内淋巴细胞作为肠道免疫的主要效应细胞
Springer Semin Immunopathol. 1997;18(4):463-75. doi: 10.1007/BF00824053.
9
The intestinal epithelial cell: immunological aspects.肠上皮细胞:免疫学方面。
Springer Semin Immunopathol. 1997;18(4):449-61. doi: 10.1007/BF00824052.
10
The immunopathology of M cells.M细胞的免疫病理学
Springer Semin Immunopathol. 1997;18(4):421-48. doi: 10.1007/BF00824051.

Intestinal IgA: novel views on its function in the defence of the largest mucosal surface.

作者信息

Mestecky J, Russell M W, Elson C O

机构信息

Department of Microbiology, University of Alabama at Birmingham, USA.

出版信息

Gut. 1999 Jan;44(1):2-5. doi: 10.1136/gut.44.1.2.

DOI:10.1136/gut.44.1.2
PMID:9862815
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1760065/
Abstract
摘要