来自细叶香茶菜的新二萜类化合物——异细叶香茶菜素A和B

[New diterpenoids, isodoternifolins A and B, from Isodon ternifolius].

作者信息

Wang Z M, Feng H, Liang X T, Yuan S T, Xu M J

机构信息

Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing.

出版信息

Yao Xue Xue Bao. 1996;31(10):764-9.

PMID:9863245

Abstract

Two new diterpenoids, named isodoternifolin A and B, together with seven known compounds were isolated from the ethanol extract of dried stems and leaves of Isodon ternifolius (D. Don) Kudo. Their structures were determined as 7 beta-hydroxy-6 beta, 11 alpha, 15 beta-triacetoxy-7 alpha, 20-epoxyentkaur-16-ene (1) and 6 beta, 7 beta, 15 beta-trihydroxy-11 alpha-acetoxy-7 alpha, 20-epoxy-entkaur-16-ene (2) by chemical and spectral evidence.

摘要

从细叶香茶菜（Isodon ternifolius (D. Don) Kudo）干燥茎和叶的乙醇提取物中分离得到两个新的二萜类化合物，命名为异细叶香茶菜素A和B，以及七个已知化合物。通过化学和光谱证据确定它们的结构分别为7β-羟基-6β,11α,15β-三乙酰氧基-7α,20-环氧对映贝壳杉-16-烯（1）和6β,7β,15β-三羟基-11α-乙酰氧基-7α,20-环氧对映贝壳杉-16-烯（2）。