3-硝基己二酸，一种红球菌新菌株将2,4-二硝基苯酚矿化的代谢中间体。
3-nitroadipate, a metabolic intermediate for mineralization of 2, 4-dinitrophenol by a new strain of a Rhodococcus species.
作者信息
Blasco R, Moore E, Wray V, Pieper D, Timmis K, Castillo F
机构信息
Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias, 14071 Córdoba,
出版信息
J Bacteriol. 1999 Jan;181(1):149-52. doi: 10.1128/JB.181.1.149-152.1999.
Abstract
The bacterial strain RB1 has been isolated by enrichment cultivation with 2,4-dinitrophenol as the sole nitrogen, carbon, and energy source and characterized, on the basis of 16S rRNA gene sequence comparison, as a Rhodococcus species closely related to Rhodococcus opacus. Rhodococcus sp. strain RB1 degrades 2,4-dinitrophenol, releasing the two nitro groups from the compound as nitrite. The release of nitro groups from 2,4-dinitrophenol occurs in two steps. First, the 2-nitro group is removed as nitrite, with the production of an aliphatic nitro compound identified by 1H nuclear magnetic resonance and mass spectrometry as 3-nitroadipate. Then, this metabolic derivative is further metabolized, releasing its nitro group as nitrite. Full nitrite assimilation upon reduction to ammonia requires that an additional carbon source be supplied to the medium.
摘要
细菌菌株RB1是通过以2,4-二硝基苯酚作为唯一氮源、碳源和能源进行富集培养而分离得到的，并根据16S rRNA基因序列比较，鉴定为与不透明红球菌密切相关的红球菌属物种。红球菌属菌株RB1降解2,4-二硝基苯酚，从该化合物中释放出两个硝基作为亚硝酸盐。从2,4-二硝基苯酚中释放硝基分两步进行。首先，2-硝基作为亚硝酸盐被去除，同时产生一种脂肪族硝基化合物，通过1H核磁共振和质谱鉴定为3-硝基己二酸。然后，这种代谢衍生物进一步代谢，释放出其硝基作为亚硝酸盐。还原为氨时完全同化亚硝酸盐需要向培养基中提供额外的碳源。
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本文引用的文献
1
Initial hydrogenation and extensive reduction of substituted 2,4-dinitrophenols.取代的 2,4-二硝基苯酚的初步加氢和广泛还原。
Appl Environ Microbiol. 1996 Mar;62(3):784-90. doi: 10.1128/aem.62.3.784-790.1996.
2
Database on the structure of small ribosomal subunit RNA.小核糖体亚基RNA结构数据库。
Nucleic Acids Res. 1997 Jan 1;25(1):111-6. doi: 10.1093/nar/25.1.111.
3
The RDP (Ribosomal Database Project).核糖体数据库项目（RDP）
Nucleic Acids Res. 1997 Jan 1;25(1):109-11. doi: 10.1093/nar/25.1.109.
4
Biodegradation of nitroaromatic compounds.硝基芳香化合物的生物降解
Annu Rev Microbiol. 1995;49:523-55. doi: 10.1146/annurev.mi.49.100195.002515.
5
Construction of a Pseudomonas hybrid strain that mineralizes 2,4,6-trinitrotoluene.构建一种能使2,4,6-三硝基甲苯矿化的假单胞菌杂交菌株。
J Bacteriol. 1993 Apr;175(8):2278-83. doi: 10.1128/jb.175.8.2278-2283.1993.
6
Two independently regulated cytochromes P-450 in a Rhodococcus rhodochrous strain that degrades 2-ethoxyphenol and 4-methoxybenzoate.在一株降解2-乙氧基苯酚和4-甲氧基苯甲酸的红平红球菌中两种独立调控的细胞色素P-450。
J Bacteriol. 1993 Mar;175(5):1467-74. doi: 10.1128/jb.175.5.1467-1474.1993.
7
Biotransformations catalyzed by the genus Rhodococcus.红球菌属催化的生物转化。
Crit Rev Biotechnol. 1994;14(1):29-73. doi: 10.3109/07388559409079833.
8
Comparative anatomy of 16-S-like ribosomal RNA.16S 样核糖体 RNA 的比较解剖学
Prog Nucleic Acid Res Mol Biol. 1985;32:155-216. doi: 10.1016/s0079-6603(08)60348-7.
9
Light-dependent degradation of nitrophenols by the phototrophic bacterium Rhodobacter capsulatus E1F1.光合细菌荚膜红杆菌E1F1对硝基酚的光依赖降解作用
Appl Environ Microbiol. 1992 Feb;58(2):690-5. doi: 10.1128/aem.58.2.690-695.1992.
10
Initial hydrogenation during catabolism of picric acid by Rhodococcus erythropolis HL 24-2.红平红球菌HL 24-2在苦味酸分解代谢过程中的初始氢化作用。
Appl Environ Microbiol. 1992 Sep;58(9):2933-7. doi: 10.1128/aem.58.9.2933-2937.1992.
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