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Low blastocyst formation rates in day-2 fertilized oocytes.第2天受精的卵母细胞中囊胚形成率较低。
J Assist Reprod Genet. 1998 Nov;15(10):594-8. doi: 10.1023/a:1020329326790.
2
Prospective, auto-controlled study on reinsemination of failed-fertilized oocytes by intracytoplasmic sperm injection.卵胞浆内单精子注射对受精失败卵母细胞进行再受精的前瞻性自身对照研究。
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Slow oocyte freezing and thawing in couples with no sperm or an insufficient number of sperm on the day of in vitro fertilization.在体外受精当天没有精子或精子数量不足的夫妇中,缓慢冷冻和解冻卵母细胞。
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Blastulation of a zygote to a hatched blastocyst without any clear cell division: an observational finding in a time-lapse system after in vitro fertilization.受精卵在体外受精后经过延时摄影系统观察到,在没有明显细胞分裂的情况下,发育成孵化的囊胚。
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Reduced blastocyst formation in reduced culture volume.培养体积减少时囊胚形成减少。
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The value of oocyte reinsemination in human in vitro fertilization.卵母细胞再受精在人类体外受精中的价值
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本文引用的文献

1
Blastocyst formation is a good indicator for attainment of assisted reproduction.
Chin J Physiol. 1997 Dec 31;40(4):237-42.
2
Optimal insemination concentration for human in vitro fertilization (IVF).人类体外受精(IVF)的最佳授精浓度
Chin J Physiol. 1997 Dec 31;40(4):227-36.
3
Culture and transfer of human blastocysts increases implantation rates and reduces the need for multiple embryo transfers.人类囊胚的培养与移植可提高着床率并减少多胚胎移植的需求。
Fertil Steril. 1998 Jan;69(1):84-8. doi: 10.1016/s0015-0282(97)00438-x.
4
Reinsemination of one-day-old oocytes by use of intracytoplasmic sperm injection.
Fertil Steril. 1996 Jul;66(1):118-21.
5
A retrospective analysis of the in-vitro development of 'spare' human in-vitro fertilization preimplantation embryos using 'in-house' prepared medium and 'Medi-Cult' commercial medium.
Hum Reprod. 1995 Nov;10(11):2976-84. doi: 10.1093/oxfordjournals.humrep.a135833.
6
Immaturity and chromosomal abnormalities in oocytes that fail to develop pronuclei following insemination in vitro.体外受精后未能形成原核的卵母细胞中的不成熟和染色体异常。
Hum Reprod. 1993 Feb;8(2):229-32. doi: 10.1093/oxfordjournals.humrep.a138028.
7
High fertilization and implantation rates after intracytoplasmic sperm injection.卵胞浆内单精子注射后具有较高的受精和着床率。
Hum Reprod. 1993 Jul;8(7):1061-6. doi: 10.1093/oxfordjournals.humrep.a138192.
8
Relationship between the developmental programs controlling nuclear and cytoplasmic maturation of mouse oocytes.控制小鼠卵母细胞核成熟与细胞质成熟的发育程序之间的关系。
Dev Biol. 1994 Jul;164(1):1-9. doi: 10.1006/dbio.1994.1175.
9
Poor fertilization may be related to oocyte or zona pellucida recognition defects specific to certain hyperstimulation regimens and limited to some males but not others: a case report.受精不良可能与某些超促排卵方案特有的卵母细胞或透明带识别缺陷有关,且仅限于部分男性而非其他男性:一例病例报告。
Fertil Steril. 1995 Jun;63(6):1341-3. doi: 10.1016/s0015-0282(16)57623-7.
10
Failed fertilization in vitro: second day micromanipulation of oocytes versus reinsemination.体外受精失败:卵母细胞第二天显微操作与再次受精的比较
Fertil Steril. 1995 Jun;63(6):1337-40. doi: 10.1016/s0015-0282(16)57622-5.

第2天受精的卵母细胞中囊胚形成率较低。

Low blastocyst formation rates in day-2 fertilized oocytes.

作者信息

Gullett J, Grunert G M, Valdes C T, Dunn R C, Wun W S

机构信息

Obstetrical and Gynecological Associates, Houston, Texas 77504-1989, USA.

出版信息

J Assist Reprod Genet. 1998 Nov;15(10):594-8. doi: 10.1023/a:1020329326790.

DOI:10.1023/a:1020329326790
PMID:9866067
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3454855/
Abstract

PURPOSE

To examine the blastocyst formation rates of day-2 fertilized oocytes.

METHODS

A retrospective study of the outcomes/blastocyst formation of day-2 fertilized oocytes was undertaken.

RESULTS

Fertilization rates of day-1 and -2 oocytes by intra-cytoplasmic sperm injection were similar. The development frequencies to four cells were similar. However, the blastulation rates were significantly lower from the day-2 fertilized eggs. The fertilization rates from day-2 conventional in vitro fertilization reinsemination were lower than the fertilization rates of day-1 oocytes. The blastulation rates from day-2 fertilized eggs were also lower than the rates from day-1 fertilized eggs in the in vitro fertilization group.

CONCLUSIONS

Fertilization is not a good indicator to predict the viability of fertilized oocytes. Day-2 fertilized oocytes had significantly lower blastocyst formation rates than the rates from day-1 fertilized oocytes.

摘要

目的

研究第2天受精卵的囊胚形成率。

方法

对第2天受精卵的结局/囊胚形成进行回顾性研究。

结果

通过卵胞浆内单精子注射,第1天和第2天卵母细胞的受精率相似。发育至4细胞的频率相似。然而,第2天受精卵的囊胚形成率显著较低。第2天常规体外受精再受精的受精率低于第1天卵母细胞的受精率。在体外受精组中,第2天受精卵的囊胚形成率也低于第1天受精卵的囊胚形成率。

结论

受精并非预测受精卵活力的良好指标。第2天受精卵的囊胚形成率显著低于第1天受精卵的囊胚形成率。