儿茶素-铜（II）配合物在无过氧化氢条件下对大肠杆菌ATCC11775的杀菌活性。

Bactericidal activity of catechin-copper (II) complexes on Escherichia coli ATCC11775 in the absence of hydrogen peroxide.

作者信息

Kimura T, Hoshino N, Yamaji A, Hayakawa F, Ando T

机构信息

Department of Chemistry, Shiga University of Medical Science, Japan.

出版信息

Lett Appl Microbiol. 1998 Dec;27(6):328-30. doi: 10.1046/j.1472-765x.1998.00458.x.

DOI:10.1046/j.1472-765x.1998.00458.x

PMID:9871350

Abstract

Washed Escherichia coli ATCC11775 cells were killed by (-)-epigallocatechin (EGC) in the presence of a non-lethal concentration of Cu2+ (1 mumol l-1) without additional H2O2, but not by (-)-epicatechin (EC). EGC alone (< 0.1 mmol l-1) did not reduce the viability of the cells. The survival curve obtained in the presence of EGC and Cu2+ was similar to that obtained in the presence of (-)-adrenaline (EN) and Cu2+.

摘要

洗涤后的大肠杆菌ATCC11775细胞在存在非致死浓度的Cu2+（1微摩尔/升）且无额外过氧化氢的情况下被（-）-表没食子儿茶素（EGC）杀死，但未被（-）-表儿茶素（EC）杀死。单独的EGC（<0.1毫摩尔/升）不会降低细胞活力。在EGC和Cu2+存在下获得的存活曲线与在（-）-肾上腺素（EN）和Cu2+存在下获得的存活曲线相似。